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Real-world of AI in Diagnosing Retinal Diseases

Real-world Application of Using Artificial Intelligence in Diagnosing Retinal Diseases

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05981950
Enrollment
100000
Registered
2023-08-08
Start date
2023-08-01
Completion date
2029-08-01
Last updated
2023-08-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Artificial Intelligence, Retinal Diseases

Brief summary

The objective of this study is to apply an artificial intelligence algorithm to diagnose multi-retinal diseases in real-world settings. The effectiveness and accuracy of this algorithm are evaluated by sensitivity, specificity, positive predictive value, negative predictive value, and area under curve.

Detailed description

The objective of this study is to apply an artificial intelligence algorithm to diagnose referral diabetes retinopathy, referral age-related macular degeneration, referral possible glaucoma, pathological myopia, retinal vein occlusion, macular hole, macular epiretinal membrane, hypertensive retinopathy, myelinated fibers, retinitis pigmentosa and other retinal lesions from fundus photography. tic 45-degree fundus cameras, trained operators took binocular fundus photography on participants. Operators were then asked to identify gradable images and unload for algorithm diagnosis. The effectiveness and accuracy of this algorithm are evaluated by sensitivity, specificity, positive predictive value, negative predictive value, area under curve, and F1 score.

Interventions

Retinal diseases diagnosed by artificial intelligence algorithm

Sponsors

Beijing Tongren Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
1 Years to 100 Years

Inclusion criteria

* fundus photography around 45° field which covers optic disc and macula * complete identification information

Exclusion criteria

* insufficient information for diagnosis

Design outcomes

Primary

MeasureTime frameDescription
Area under curve1 monthWe used the receiver operating characteristic (ROC) curve and area under curve to examine the ability of this artificial intelligence algorism recognition and classification of retinal diseases.
Sensitivity and specificity1 monthWe used sensitivity and specificity to examine the ability of this artificial intelligence algorism recognition and classification of retinal diseases.
Positive predictive value, negative predictive value1 monthWe used positive predictive value and negative predictive value to examine the ability of this artificial intelligence algorism recognition and classification of retinal diseases.
F1 score1 monthWe used F1 score to examine the ability of this artificial intelligence algorism recognition and classification of retinal diseases.

Countries

China

Contacts

Primary ContactWenbin Wei, MD
weiwenbintr@163.cim58269516
Backup ContactRuiheng Zhang, MD
zhangruihengsy@outlook.com18801121782

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026