Nonsuicidal Self Injury, Prediction Errors
Conditions
Brief summary
Nonsuicidal self-injury (NSSI) is defined as direct, intentional physical injury without suicidal intention. Studies revealed that dysfunctional interpersonal relationships and reward-related decision-making may play crucial roles in this maladaptive behavior, especially in adolescents. These interpersonal decision contexts are characterized by constant updating of expectations of rewards and the actual received rewards as well as the associated emotional reactions. These processes have recently been computationally formalized as prediction errors (PE), specifically reward PEs, valence PEs, and arousal PEs (Heffner et al., 2021; Nat Hum Behav). In the current study, the investigators aim to investigate whether these PEs make discernible contributions to social decisions in the context of unfair experiences among adolescents with NSSI and matched healthy control adolescents (HC). Specifically the investigators hypothesized that: 1) reward and emotional PEs show significant predictions of punishment decisions in both groups, 2) however, compared to HC adolescents, the NSSI group will exhibit selective dysfunctions in emotional but not reward PEs leading to punish a norm proposer who provided unfair offers.
Interventions
None listed
Sponsors
University of Electronic Science and Technology of China
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
15 Years to 18 Years
Inclusion criteria
* 15-18 years * right-handed * normal or corrected normal visual acuity * meet the proposed DSM-5 frequency criteria (e.g., ≥5 days of NSSI behaviors in the past year)
Exclusion criteria
* diagnosis of borderline personality disorder, major depressive disorder, other * psychiatric disorders, etc. * high suicidal risk * recent use of medications that can affect neural activity * have received or are receiving Dialectical Behavior Therapy (DBT) other treatment for emotional problems within the past 6 months * have a contraindication to MRI scanning (e.g., metal implants, claustrophobia or other conditions that make them inappropriate for MRI scanning)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Reward prediction errors (PEs) | About 20 minutes | Reward PEs will be calculated by the differences between the experienced (when be offered) reward and predicted (before the offer) reward. |
| Valence prediction errors (PEs) | About 20 minutes | Valence PEs will be calculated by the differences between the experienced emotional valence and predicted emotional valence. |
| Arousal prediction errors (PEs) | About 20 minutes | Arousal PEs will be calculated by the differences between the experienced emotional arousal and predicted emotional arousal. |
| The prediction of PEs of punishment decisions | About 20 minutes | All PEs and groups (NSSI, HC) will be used in a regression model to examined whether there is any alteration in the NSSI group when PEs are predicted to punishment (reject) decisions. |
Countries
China
Contacts
Primary ContactBenjamin Becker
Outcome results
None listed