Disparities Among Liver Transplant Patients

Individual and Structural-level Determinants Associated With Disparities Among Liver Transplant Patients

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05981196

Enrollment

100

Registered

2023-08-08

Start date

2023-11-15

Completion date

2026-10-31

Last updated

2026-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

End Stage Liver DIsease

Keywords

Transplants, Transplantation, Healthcare Disparities, Minority Health, Communication

Brief summary

The purpose of this study is to inform healthcare interventions to reduce the disparities in liver transplant listing and in transplantation.

Detailed description

Aim 1. Establish a longitudinal cohort of patients with end-stage liver dysfunction. Aim 2. Examine interpersonal and structural factors associated with liver transplant evaluation and listing by patient characteristics (e.g., race, ethnicity, SES, gender). Aim 3. Examine the use of stigmatizing language among patients undergoing liver transplant based on their demographic characteristics (e.g., race, ethnicity, SES, gender).

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Inclusion criteria

\- Patients with end-stage liver, kidney, or cardiac dysfunction.

Exclusion criteria

* Patients with more than one system with end stage organ dysfunction, dementia, cognitive or sensory impairment, prior solid organ transplant. * Patients with potential medical exclusions for transplant.

Design outcomes

Primary

Measure	Time frame	Description
Liver transplant waiting list	Approximately one year	Number of subjects listed on the liver transplant waiting list
Organ transplantation	Approximately one year	Number of subject to receive an organ transplantation

Secondary

Measure	Time frame	Description
Graft survival at six months	Six months post transplant	Total number of subject to have a functioning graft at six months post transplant
Graft survival at one year	One year post transplant	Total number of subject to have a functioning graft at one year post transplant
Survival	Approximately one year post-transplant, or until you are removed from the transplant list	Total number of subject alive

Countries

United States

Contacts

PRINCIPAL_INVESTIGATORPeter E. Frasco, MD

Mayo Clinic

Outcome results