Neoplasms
Conditions
Keywords
Neoplasms, Exercise Therapy, Side Effects, Cancer-related Fatigue, Quality of Life
Brief summary
Cancer survival rates are currently on the verge of 70% at 5 years since diagnosis. Recent improvements in main cancer therapies including chemotherapy, radiotherapy, surgery and immunotherapy as well as developments of new biological therapies have significantly improved survival rates but unfortunately, cancer-related side effects continue to affect many patients even years after completion of main treatments. Exercise has been shown to not only ameliorate cancer-related effects before, during and after treatment but also improve disease-free and overall survival rates by decreasing risk factors associated with cancer risk and improving resilience to treatment. In this non-randomised, three-arm study, we aim to assess the effects of three forms of exercise (i.e: Nordic Walking, Aquatic Exercise and Functional Exercise) on physical performance, cancer-related fatigue, health-related quality of life and cancer-specific symptoms in a wide range of cancer survivors.
Interventions
BEHAVIORALNordic Walking
A 12-week Nordic Walking exercise programme supervised twice weekly
BEHAVIORALAquatic Exercise
A 12-week water-based exercise training programme supervised twice weekly
BEHAVIORALFunctional Exercise Training
A 12-week circuit-based exercise training programme supervised twice weekly
Sponsors
Col·legi de Fisioterapeutes de Catalunya
Ajuntament de Mataró
Universitat Pompeu Fabra
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adults diagnosed with cancer * Completion of any cancer therapy in the previous 3 months with the exception of hormonal therapy * Patients living within the Maresme Area * No contraindications for exercise (oncology clearance or Physical Activity Readiness Questionnaire negative)
Exclusion criteria
* Patients with any neurologic, cognitive or musculoskeletal impairments that prevent them to engage in any assessment test or exercise modality. * Patients with unstable cardiac, respiratory or metabolic diseases * Unable to speak or read Catalan or Spanish
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Health-Related Quality of Life | 12 weeks from baseline | HRQoL measured with the EORTC Quality of Life C30 questionnaire |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Cancer-related fatigue | 12 weeks from baseline | Cancer-related fatigue as measure with the Brief Fatigue Inventory |
| Cardiorespiratory fitness | 12 weeks from baseline | A steady state cardiopulmonary exercise testing with breath-by-breath analysis and lactate measurement to determine submaximal cardiorespiratory fitness |
| Estimated one-repetition maximum | 12 weeks from baseline | Estimated maximal muscle strength using a linear Encoder for two main muscle groups: i) chest and ii) quads |
| Lower limb muscle endurance | 12 weeks from baseline | Lower limb muscle endurance measured as the maximum number of sit-to-stand repetitions performed in 30 seconds |
| Functional capacity | 12 weeks from baseline | Walking distance covered during a self-pace 6 minute walk test |
Contacts
Primary ContactEsther Mur Gimeno, PhD
Backup ContactRaquel Sebio García, PhD
Outcome results
None listed