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Novamin on Streptococcus Mutans Count in Dental Plaque of High Caries Risk Children

Effect of Toothpaste Containing Novamin on Streptococcous Mutans Count in Dental Plaque of High Caries Risk Children (Randomized Controlled Clinical Trial)

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05979636
Enrollment
36
Registered
2023-08-07
Start date
2022-12-06
Completion date
2023-01-01
Last updated
2023-08-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental Caries, Dental Plaque

Brief summary

Inhibition of streptococcus mutans can be effective to prevent caries in high caries-risk children. The aim of the study is to evaluate the effect of Novamin on streptococcus mutans in the plaque of high caries-risk children.

Interventions

children's teeth will be brushed using Novamin containing toothpaste.

OTHERFluoride containing toothpaste

children's teeth will be brushed using Fluoride containing toothpaste.

Sponsors

Hams Hamed Abdelrahman
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
3 Years to 6 Years
Healthy volunteers
No

Inclusion criteria

* Medically healthy children. * No erupting first permanent molars. * High caries risk children; Have visible cavities or have a visible plaque on their teeth. * Cooperative (Positive or definitely positive), according to Frankl's Behavior Rating Scale

Exclusion criteria

* History of intake of antibiotics for the past 3-4 weeks. * History of professional fluoride treatment over 2 weeks before the study. * Children with tooth structure defects. * Children unable to return for recall visits

Design outcomes

Primary

MeasureTime frameDescription
Change in bacterial count in dental plaque1 week, 2 weeks and 4 weeksThe samples will be collected from all children in the study and the level of S.mutans will be recorded.

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026