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Determining How Indoor Lighting Affects the Brain Health of Older Adults

Determining How Indoor Lighting Affects the Brain Health of Older Adults

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05978934
Enrollment
70
Registered
2023-08-07
Start date
2023-05-15
Completion date
2023-12-31
Last updated
2023-08-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cognitive Function, Physical Activity, Sleep, Social Isolation

Brief summary

The goal of this randomized, cross-over, single-site trial followed by an exploratory third intervention is to understand how indoor lighting affects different measures of brain health in older adults living in independent living residences. This is a community based study occurring in a local senior living facility. The main question this study aims to answer is: \- How does the quality of ambient indoor lighting an older adult is exposed to affect measures of brain health, such as sleep quality, physical activity, cognitive function, and social engagement? Participants will be exposed to three different indoor lighting conditions for 4 weeks each while performing the following tasks: * Wear a smartwatch throughout the study to measure sleep quality and physical activity * Wear a small, wearable light sensor to measure light exposure during waking hours * Perform cognitive assessments throughout the study to detect any changes between each of the lighting conditions * Complete self-report of surveys to assess independence, social engagement, sleep quality, and mood Results from these tasks will be compared within and between subjects to assess whether the different lighting conditions affect these different measures of brain health.

Interventions

BEHAVIORALStatic Lighting Condition (L1)

This indoor lighting condition keeps a constant brightness and correlated color temperature.

BEHAVIORALDynamic Lighting Condition (L2)

This indoor lighting condition has increased brightness and more blue correlated color temperature in the morning hours followed by decreased brightness and less blue correlated color temperature in the afternoon and evening hours.

BEHAVIORALDynamic Lighting Condition (L3)

This exploratory indoor lighting condition matches the same pattern as L2 except the brightness in the morning hours is increased.

Sponsors

Mayo Clinic
CollaboratorOTHER
Well Living Lab, Inc.
Lead SponsorINDUSTRY

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
60 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

1. At least age 60; 2. Able to wear wearable devices throughout the study; 3. Willing to have their lighting in their kitchen and dining areas changed and controlled for the study; 4. Willing to have environmental sensors placed in their residence; 5. Willing to provide contact information about their primary care provider (PCP); and 6. Able and has capacity to provide informed consent (score \> 14.5 based on UBACC consent capacity form).

Exclusion criteria

1. Is legally blind 2. Previously renovated their living units and no longer have the standard lighting installation offered by the Senior Living Facility; 3. Currently spend or plan to spend most of their day outside of their residence during the study (i.e., would not experience the indoor lighting intervention for the majority of the study); 4. Plan to travel to a different time zone during the study; or 5. Plan to be away from their residence for more than a week during the study.

Design outcomes

Primary

MeasureTime frameDescription
Total Sleep TimeChange in total sleep time per night over the course of each condition of the 16-week study.Total sleep time per night in minutes as measured daily by a wearable device.
Wake After Sleep OnsetChange in wake after sleep onset per night over the course of each condition of the 16-week study.Wake after sleep onset per night in minutes as measured daily by a wearable device.
Sleep State DurationChange in sleep state duration per night over the course of each condition of the 16-week study.Sleep state duration per night in minutes as measured daily by a wearable device.

Secondary

MeasureTime frameDescription
Working MemoryChange in working memory performance over the course of each condition of the 16-week study.Task performance on a working memory assessment taken twice weekly.
Task SwitchingChange in task switching performance over the course of each condition of the 16-week study.Task performance on a task switching assessment taken twice weekly.
Response InhibitionChange in response inhibition performance over the course of each condition of the 16-week study.Task performance on a response inhibition assessment taken twice weekly.
Sleep QualityChange in self-reported sleep quality over the course of each condition of the 16-week study.Self-report measurement of perceived sleep quality made daily via the Groningen Sleep Quality Survey.
Self-Reported LonelinessChange in self-reported loneliness over the course of each condition of the 16-week study.Self-report measurement of loneliness assessed weekly via the UCLA Loneliness Scale.
Self-Reported DepressionChange in self-reported depression over the course of each condition of the 16-week study.Self-report measurement of depression assessed weekly via the Positive and Negative Affect Scale.
Self-Reported MoodChange in self-reported mood over the course of each condition of the 16-week study.Self-report measurement of mood assessed weekly via the Depression, Anxiety, and Stress Scale.
Sustained-Attention Reaction TimeChange in sustain-attention reaction time performance over the course of each condition of the 16-week study.Task performance on a sustained-attention reaction time assessment taken twice weekly.
Steps TakenChange in physical activity in steps per day over the course of each condition of the 16-week study.Physical activity in steps per day as measured daily by a wearable device.
Physical ActivityChange in physical activity in minutes per day over the course of each condition of the 16-week study.Physical activity in minutes per day as measured daily by a wearable device.

Countries

United States

Contacts

Primary ContactRobert Klein, PhD
robert.klein@delos.com507-258-7592
Backup ContactEric Heins
eric.heins@delos.com507-259-0611

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 5, 2026