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A Prospective Cohort Study of for Surgical Treatment of Irreducible Atlantoaxial Dislocation

A Prospective Cohort Study of for Surgical Treatment of Irreducible Atlantoaxial Dislocation

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05978375
Enrollment
100
Registered
2023-08-07
Start date
2023-09-01
Completion date
2025-09-01
Last updated
2023-08-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atlantoaxial Dislocation

Brief summary

The management of irreducible atlantoaxial dislocation associated is challenging. Direct posterior distraction technique we proposed in 2010 could achieve satisfactory reduction. In 2020, we modified this technique and proposed a posterior intra-articular distraction technique. The intra-articular distraction technique could theoretically achieve satisfactory reduction and fusion. However, its superiority has not been proven. Therefore, we design a prospective study to compare the reduction rate and fusion rate of different strategies.

Interventions

PROCEDUREPosterior intra-articular distraction and fusion

Using reduction using posterior intra-articular distraction and fusion technique.

PROCEDUREAnterior transoral release and posterior cantilever reduction and fusion

Using anterior transoral release and posterior cantilever reduction and fusion technique.

PROCEDURETARP

Using TARP technique.

Sponsors

Xuanwu Hospital, Beijing
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No

Inclusion criteria

CT indicated atlantoaxial dislocation Agree with the operation plan Agree to be followed up

Exclusion criteria

The pathology is traumatic or RA Underwent operations in occipital-cervical region before With mortal diseases Without ability to sign papers

Design outcomes

Primary

MeasureTime frameDescription
Fusion Rates12 monthsAtlantoaixal fusion rates

Secondary

MeasureTime frameDescription
Japanese Orthopaedic Association Scores12 months0-17 Scores
Visual Analogue Scale12 months0-10 Scores
Neck Disability Index12 months0-5 Scores

Contacts

Primary ContactZan Chen, MD
chenzan66@163.com+8613911712120

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026