Serum Lipase and Severity of Pancreatic Injury.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05978076

Enrollment

Registered

2023-08-07

Start date

2021-12-01

Completion date

2021-12-30

Last updated

2023-08-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pancreatic Injury

Keywords

Lipase, Pancreatic trauma, Pseudocysts

Brief summary

Diagnosis of pancreas injury is not easy at first consult. It's a retrospective study, in children under 15 years and 3months, between January 1st 2010 to August 31th 2019, to prove that the first level of lipase is correlated with the severity of pancreatic injury. Every children with elevated serum lipase after trauma during those years will be selected. The children with pancreatic tumors will be excluded. American Association of Surgeon Trauma (AAST) classification of pancreas injury will be used to grade severity. Children will be divided in two groups : one including pancreatic lesion with duct injury and one without duct injury. Data will include mechanism of injury, associated injury, length of stay, maximal lipase level, nutritional care and local complications will be noted.

Detailed description

The main objective of this study is to determine if there is a correlation between the initial serum lipase and the severity of the pancreatic injury.

Interventions

OTHERdata collection

data collection : mechanism of injury, associated injury, length of stay, maximal lipase level, nutritional care and local complications.

Study design

Observational model

CASE_ONLY

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

No minimum to 15 Years

Healthy volunteers

Inclusion criteria

* Children under 15 years 3 months with elevated lipase serum level after trauma.

Exclusion criteria

* Elevation of lipase secondary to pancreatic tumor

Design outcomes

Primary

Measure	Time frame	Description
lipase level in severe pancreatic injury (duct injury)	Month: 9 (end of study)	Collected in medical history.
lipase level in light pancreatic injury (without duct injury)	Month: 9 (end of study)	Collected in medical history.

Secondary

Measure	Time frame	Description
Local complications	Month: 9 (end of study)	Collected in medical history.
Maximal lipase level	Month: 9 (end of study)	Collected in medical history.

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026