Time Effect on the Predictability of Different Grafting for Gingival Recession RT 1

Time Effect on the Predictability of Different Grafting Materials in Treatment of Gingival Recession RT 1in the Esthetic Zone

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05976451

Enrollment

Registered

2023-08-04

Start date

2020-10-01

Completion date

2023-03-03

Last updated

2023-11-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gingival Recession Types One(RT1)

Brief summary

The primary objective of this study was to evaluate time effect on the clinical predictability of collagen matrix Xenograft (CMX) with melatonin gel versus connective tissue graft (CTG) and determine whether it is proposed to be an alternative in multiple adjacent gingival recession (MAGR) in recession type one (RT1)

Detailed description

this study was conducted to evaluate time effect on the clinical predictability of collagen matrix Xenograft (CMX) with melatonin gel versus connective tissue graft (CTG) and determine whether it is proposed to be an alternative in multiple adjacent gingival recession

Interventions

COMBINATION_PRODUCTmelatonin with collagen matrix

(CMX) with melatonin in the esthetic zone using Modified Coronally Advanced Tunneling Technique (MCAT)

COMBINATION_PRODUCTconnective tissue graft (CTG)

control group connective tissue graft using Modified Coronally Advanced Tunneling Technique (MCAT)

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

19 Years to 40 Years

Healthy volunteers

Yes

Inclusion criteria

* Presence of RT1 GRs of the maxillary or mandibular arch in the esthetic zone with a GR depth ≥2 mm, * patients \>18 years old, * Full mouth plaque index score \<20% * Systemically and periodontally healthy patients.

Exclusion criteria

* Smokers * Patients with periodontitis stage III and IV were previous surgical treatment of GR, * Pregnant or breastfeeding women; P * Patients with para-functional habits or any source of occlusal trauma.

Design outcomes

Primary

Measure	Time frame	Description
interproximal clinical attachment level	6-9 months	measured from CEJ to base of pocket depth by using periodontal prob
Probing pocket depth (PPD)	6-9 months	from gingival margin to pocket depth measured by mm
Recession depth	6-9 months	measure from CEJ to gingival margin by mm

Secondary

Measure	Time frame	Description
Keratinized tissue width	6-9 months	from free gingival groove to MGJ

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026