Post Operative Sore Throat
Conditions
Brief summary
Sore throat includes specific symptoms such as dysphagia, dysphonia, hoarseness, continuous throat pain, and pharyngeal dryness. Patients rated postoperative sore throat (POST) as the eighth most undesirable outcome in the postoperative period POST has a reported incidence of up to 62% following general anesthesia (GA). The incidence of POST is more common in GA with tracheal intubation than in GA with the supraglottic airway Ketamine is an N-methyl-D-aspartate (NMDA) receptor antagonist and has been used as a gargle for reducing the incidence and severity of POST due to its anti-nociceptive and anti-inflammatory effects
Interventions
DRUGKetamine
description
OTHERsaline nebulization
description
Sponsors
Sohag University
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
16 Years to 60 Years
Inclusion criteria
1. Age 16-60 years. 2. Of both sex. 3. American Society of Anesthesiologists Physical Status (ASA PS) I-II. 4. Undergoing general anesthesia with endotracheal intubation with surgery duration less than two hours.
Exclusion criteria
* a- History of chronic obstructive History of sore throat or upper respiratory tract infection. b- Intraoral and intrapharyngeal surgery. c- airway disease or Asthma. d- Mallampati grade more than II. e- Known allergic to study drug. f- More than one attempt is required for intubation. g- Hypertensive patients. h- Epileptic patients. i- cerebral palsy or any neurological disorders. j- Psychiatry patients. k- Cardiac patients. l- Perioperative use of anti-inflammatory drugs (Non-steroidal anti-inflammatory drug or steroids).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| the incidence and severity of POST | at immediate recovery (0 h), 2, 4, 6, 8, 12 and 24 h post-operatively. | the study is to measure the incidence and severity of POST at immediate recovery (0 h), 2, 4, 6, 8, 12 and 24 h post-operatively. in adult patients undergoing surgery of a duration less than 2h. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| evaluation of side effects including nausea, vomiting, cough, and dry mouth in both groups. | at immediate recovery (0 h), 2, 4, 6, 8, 12 and 24 h post-operatively. | evaluation of side effects including nausea, vomiting, cough, and dry mouth in both groups. |
Contacts
Primary ContactDoaa A Abdellatif, resident
Backup Contactfawzy A Badawy, assistant professor
Outcome results
None listed