Ulcerative Colitis
Conditions
Brief summary
Ulcerative colitis (UC) is a refractory disease characterized by symptoms such as diarrhea, bloody stools, and abdominal pain with repeated relapses and remissions.
Detailed description
Evaluation of UC activity is important, and endoscopic evaluations of mucosal inflammation can facilitate subsequent prognostication. On the basis of these considerations, achievement of mucosal healing is important in inflammatory bowel disease (IBD), and evaluation of IBD using endoscopy is extremely important. However, endoscopic examinations are associated with problems such as physical burden to the patient, cost, and risk of complications. Thus, to avoid the need for frequent endoscopy, noninvasive biomarkers that accurately reflect the endoscopic activity of UC have emerged, and fecal calprotectin (FC) and the fecal immunochemical occult blood test (FIT) are being widely used in clinical practice.
Interventions
DIAGNOSTIC_TESTOncostatin M
Test to diagnosis of Ulcerative colitis
Sponsors
Beni-Suef University
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Healthy volunteers
Yes
Inclusion criteria
* All patients aged \>18 years and \<80 years, of both gender who diagnosed to have UC and given the consent for participation in the study
Exclusion criteria
* 1- Any patient with systemic inflammation as Bronchial asthma. 2- History of cancer or tumor. 3- Autoimmune disease such as rheumatoid arthritis and systemic lupus erythematous
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Identify if oncostatin M is a good marker | 6 months | Diagnosis of Ulcerative colitis and follow up |
Outcome results
None listed