Movement Disorders, Multiple Sclerosis
Conditions
Keywords
Multiple sclerosis, Movement Disorders
Brief summary
The aim of this study is to determine the prevalence of movement disorders in MS patients. Also,To know the clinical type of movement disorders occurring with multiple sclerosis patients and the MRI finding of those patients. Moreover, to find the correlation between the movement disorder and the different types of MS.
Detailed description
A randomized cross-sectional study will be conducted on diagnosed multiple sclerosis patients who were diagnosed according to McDonald criteria of MS 2017 (Thompson et al. 2018). The investigators will study the prevalence of movement disorders in M.S patients, clinical type of movement disorder and the MRI findings. Data collected from patients admitted or following at Al-Azhar university hospitals at Al-Hussein and El-Sayed Galal hospitals. The included eligible patients should fulfil the following inclusion criteria: i. Full clinical history and neurological assessment. ii. Detailed multiple sclerosis history according to MS unit history sheet. iii. Detailed history of movement disorder which include clinical type of movement disorder and medication taken (or not). iv. MRI Brain and spine of the included patient will be photographed. Exclusion criteria: 1. Patients with multiple sclerosis mimics which can cause movement disorders e.g., systemic disease or overlap syndromes including systemic lupus, vasculitis, hepatic failure, renal failure, hyperthyroidism, electrolyte disturbances, Behcet's disease or CNS infection. 2. patients with primary movement disorders or related to other neurodegenerative diseases.
Interventions
OTHERScreen for movement disorder and correlates it with MRI findings.
* To determine the prevalence of movement disorders in MS patients. * To know the clinical type of movement disorders occurring with multiple sclerosis patients and the MRI finding of those patients. * To find the correlation between the movement disorder and the different types of MS.
Sponsors
Al-Azhar University
Study design
Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 55 Years
Healthy volunteers
No
Inclusion criteria
\- We will study the prevalence of movement disorders in M.S patients, clinical type of movement disorder and the MRI findings. Data collected from patients admitted or following at Al-Azhar university hospitals at Al-Hussein and El-Sayed Galal hospitals. The included eligible patients should fulfil the following inclusion criteria: i. Full clinical history and neurological assessment. ii. Detailed multiple sclerosis history according to MS unit history sheet. iii. Detailed history of movement disorder which include clinical type of movement disorder and medication taken (or not). iv. MRI Brain and spine of the included patient will be photographed.
Exclusion criteria
\- 1-Patients with multiple sclerosis mimics which can cause movement disorders e.g., systemic disease or overlap syndromes including systemic lupus, vasculitis, hepatic failure, renal failure, hyperthyroidism, electrolyte disturbances, Behcet's disease or CNS infection. 2-patients with primary movement disorders or related to other neurodegenerative diseases.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Determine the prevalence of movement disorders in MS patients. | Through study completion, an average of 1.5 year | To know the percentage of occurance of movement disorders in MS patients. |
| know the clinical type of movement disorders occurring with multiple sclerosis patients and the MRI finding of those patients. | Through study completion, an average of 1.5 year | To know the specific semiology for each movement disorder. |
| find the correlation between the movement disorder and the different types of MS. | Through study completion, an average of 1.5 year | To know if there is a correlation between the movement disorder and the different types of MS. |
Countries
Egypt
Outcome results
None listed