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Community-based Communication for Blood Donation in Ghana

Community-based Communication Interventions for Increasing Repeat Donation Among First- Time Blood Donors in Ghana: A Pragmatic Type 1 Effectiveness- Implementation Hybrid Trial

Status
Active, not recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05973890
Acronym
C-CAD
Enrollment
882
Registered
2023-08-03
Start date
2024-01-15
Completion date
2026-03-30
Last updated
2025-07-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Increase Repeat Blood Donation Attempts Among First-time Donors

Brief summary

A randomized controlled trial to evaluate the effectiveness of the WhatsApp groups or docudrama compared to a control group (usual engagement with blood services) on repeat blood donation attempts among first-time blood donors in Ghana. Secondary outcomes will be blood donor retention, blood donation knowledge, attitudes, beliefs, motivations, intention to donate, and relatedness as potential mediators of blood donation behavior among first-time blood donors. The RCT will have three arms: 1. WhatsApp; 2. docudrama; 3. control. Each participant in the WhatsApp and docudrama arms will receive the intervention for 14 months. Participants in the control arm will receive standard national blood donation communications and be followed for 14 months. Actualized blood donation is possible every four months using NBSG guidelines; consequently, participants may make multiple blood donation attempts. Return blood donation attempts will be evaluated using the Southern Zonal Blood Center (SZBC) records (primary outcome) and participant self-report (secondary outcome) at 7 months and 14 months. Secondary measures will be evaluated at baseline, 7 and 14 months from enrollment. The duration of the RCT will be 26 months allowing for 12 months to achieve enrollment goals and 14 months of follow-up for the last individual enrolled.

Interventions

BEHAVIORALWhatsApp

Participants assigned to the WhatsApp arm will receive messages, audios, images and videos in a moderated, closed WhatsApp group over a 14-month duration. The messages aim to motivate blood donation, encourage participants to discuss their blood donation experiences, and allow them to share their motivations for donating blood.

BEHAVIORALdocudrama

Participants randomized to this arm will meet three times (Month 2; Month 5 and Month 10), in a group setting, during the intervention. Each group will have a maximum of 20-40 participants. This is a stand-alone activity, which is not associated with a donation event. During each meeting, participants will be asked to watch, in the group setting, an episode of drama, lasting 15 minutes. The docudrama on blood donation will address participant's concerns regarding blood donation and address common donor fears.

Sponsors

National Heart, Lung, and Blood Institute (NHLBI)
CollaboratorNIH
National Blood Service Ghana
CollaboratorOTHER
University of Ghana
CollaboratorOTHER
Syracuse University
CollaboratorOTHER
Liverpool School of Tropical Medicine
CollaboratorOTHER
University of Minnesota, Coordinating Centers for Biometric Research
CollaboratorUNKNOWN
University of Minnesota
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE

Intervention model description

parallel 3 arm randomized controlled study with equal allocation

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes

Inclusion criteria

* At least 18 years-old * First-time whole blood donor with the SZBC of the NBSG * Eligible to donate again at the time of eligibility confirmation * Consent to participate * Understands one of English, Twi, or Ga * Have a smart phone * Have, or be willing to sign up for an active WhatsApp account * Be willing to watch a docudrama on blood donation in a group setting

Exclusion criteria

* History of more than one lifetime whole blood donation (with any blood center)

Design outcomes

Primary

MeasureTime frameDescription
Proportion with a repeat donation attempt14 monthsThe primary outcome for the RCT will be the number of blood donation attempts

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026