Efficacy of VRx MyBiotics Oral Lozenges

Testing the Efficacy of VRx MyBiotics Oral Lozenges to Improve the Oral Microbiome

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05972330

Enrollment

Registered

2023-08-02

Start date

2023-06-26

Completion date

2024-01-26

Last updated

2024-02-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral Microbiome Health

Keywords

oral health, oral lozenge, oral microbiome

Brief summary

This study will test the efficacy of Viome's VRx MyBiotics Oral Lozenges at improving the oral microbiome.

Detailed description

This is a single arm, interventional trial on adults residing in the United States. The study will test the efficacy of personalized oral biotic lozenges (VRx MyBiotics Oral Lozenges) at improving oral microbiome health according to Viome's Oral Health Score.

Interventions

DIETARY_SUPPLEMENTVRx MyBiotics Oral Lozenges

VRx MyBiotics Oral Lozenges are composed of prebiotics, probiotics, and postbiotics.

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

SUPPORTIVE_CARE

Masking

NONE

Masking description

None, Open Label

Intervention model description

Participants will be assigned an oral lozenge formulation based on the baseline analysis of their oral microbiome.

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Any person with a US address that is 18 years old or older * Able to speak and read English * Willing and able to follow the trial instructions, as described in the recruitment letter * Signed and dated informed consent prior to any trial-specific procedures.

Exclusion criteria

* Systemic antibiotic treatment 30 days prior to enrollment or during the trial * Not willing to stop sporadic use (less frequently than daily) of any mouthwash. * Significant diet, supplements, or lifestyle change in the previous 1 month or next 2 months once enrolled * Allergy to tapioca, peppermint, or sweet potato * Current diagnosis of periodontitis or other advanced oral disease (chronic recurrent caries, oral cancer, etc) * No dental procedures 30 days prior to enrollment or during the trial (regular cleanings, bone grafts, dental implants, etc) * Pregnancy or planned pregnancy * Currently have cancer or undergoing cancer therapy * Dentures * Fewer than 20 teeth * Use of at home teeth whitening products 30 days prior to enrollment or during the trial * Start new medications or supplements during the trial

Design outcomes

Primary

Measure	Time frame	Description
Viome Oral Health Score	~ 4 months	Increase in oral health score as measured by Viome's Oral Health Score.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026