Pulmonary Disease
Conditions
Keywords
flexible bronchoscopy, topical airway anesthesia
Brief summary
The goal of this randomized control trial is to evaluate the effectiveness and safety of using a spray nozzle, compared to the conventional method, for topical anesthesia by the spray-as-you-go technique in reducing cough frequency, improving cough, discomfort, tolerance, satisfaction, reducing the dosage of lidocaine consumption of patients during flexible bronchoscopy.
Interventions
DEVICEWashing Pipe With a Spray Nozzle
Administration of topical airway anesthesia via a washing pipe with a spray nozzle using the spray-as-you-go technique
Sponsors
National Taiwan University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE (Subject, Outcomes Assessor)
Masking description
Patients will be randomly allocated into one of the two groups by the randomization module in REDCap. Patients and outcomes assessor will be blinded to their grouping.
Intervention model description
Group S patients will receive topical lidocaine anesthesia via the spray nozzle by the spray as-you-go technique during flexible bronchoscopy. Group C patients will receive topical lidocaine anesthesia with the conventional method by the spray as-you-go technique during flexible bronchoscopy.
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Age 18 years or older 2. A planned flexible bronchoscopy 3. Being able to communicate with Mandarin Chinese or Taiwanese Hokkien
Exclusion criteria
1. are unwilling to join the study 2. have tracheostomy or are intubated 3. will receive intravenous anesthesia during flexible bronchoscopy 4. known to be pregnant
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Cough rate | Through the duration of the bronchoscopy exam, an average of 30 min | The bronchoscopy procedure will be audio-taped throughout and cough counting will be recorded by an investigator blinded to the patient information and grouping. The cough rate will be calculated as total cough counts divided by procedure time in minute. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Adverse events | Through the duration of the bronchoscopy exam, an average of 30 min | Development of adverse events during the bronchoscopic procedure, such as bleeding and oxygen desaturation |
| Procedure time | Through the duration of the bronchoscopy exam, an average of 30 min | The duration (minute) of the bronchoscopic procedure |
| Lidocaine dosage | Through the duration of the bronchoscopy exam, an average of 30 min | Total lidocaine doses dispensed during the bronchoscopic procedure |
| Patient tolerance | Through the duration of the bronchoscopy exam, an average of 30 min | Using a visual analogue scale from 0 to 10 to indicate patient tolerance of the bronchoscopy |
| Patient satisfaction | Through the duration of the bronchoscopy exam, an average of 30 min | Using a visual analogue scale from 0 to 10 to indicate patient satisfaction of the bronchoscopy |
Countries
Taiwan
Outcome results
None listed