Macular Degeneration Choroidal Neovascularization
Conditions
Brief summary
To evaluate the activity of neovascular macula degeneretion as assessed by SD-OCTand OCT-A using a split-person study design and deep-learning quantification.
Detailed description
Exudative neovascular macular degeneration is the primarily an age-related retinal condition The optical coherence tomography angiography represents a novel and noninvasive diagnostic technique that allows a detailed and quantitative analysis of retinal and choriocapillary vascular features in order to choose the best therapy . The study evaluates the changes in structural optical coherence tomography and optical coherence tomography angiography features in neovascular macular degeration patients undergoing ANTI-VEGF treatments using artificial intelligence.
Interventions
DIAGNOSTIC_TESTDiagnostic test: using artificial intelligence to evaluate the changes OCT and OCTA parameter
Diagnostic test: using artificial intelligence to evaluate the changes OCT and OCTA parameter before and after ANTI-VEGF treatment
Sponsors
Federico II University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
50 Years to 90 Years
Healthy volunteers
Yes
Inclusion criteria
age older than 50 years * diagnosis of neovascular macular degeneration * absence of previous retinal surgery and congenital eye diseases. * absence of errors of refraction * absence of lens opacities * absence of low-quality OCT and OCTA images
Exclusion criteria
• age younger than 50 years * previous retinal surgery and congenital eye diseases * errors of refraction * lens opacities * low-quality OCT and OCTA images
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The measurements of retinal and choriocapillary vessel density in patients with macular degeneration complicated by nvc | more than sixmonths |
Countries
Italy
Outcome results
None listed