Carpal Tunnel Syndrome
Conditions
Brief summary
This is an observational study to investigate the electromyographic (EMG) activity and nerve conduction velocity (NCV) of healthy individuals during the Tinel's Sign performed at different wrist positions. The study aims to identify the wrist position that best isolates median nerve activity during the Tinel's Sign.
Detailed description
The study will be conducted in a controlled laboratory setting, equipped with an electromyography (EMG) machine and a nerve conduction velocity (NCV) measurement device. We will recruit 30 healthy adults, aged 18-45 years, with no history of hand or wrist pain, neurological or muscular disorders. Participants will be excluded if they have any contraindications to EMG or NCV measurement. The independent variable will be the wrist position during the Tinel's Sign, and the dependent variables will be the EMG activity of the thenar and hypothenar muscles and the NCV of the median and ulnar nerves. EMG activity will be measured using surface electrodes placed on the thenar and hypothenar muscles. NCV will be measured using a standard NCV measurement device. To minimize bias, the same trained examiner will perform all tests and measurements, and the examiner will be blinded to the EMG and NCV data during the tests. Differences in EMG activity and NCV across different wrist positions will be analyzed using repeated measures ANOVA. Post-hoc pairwise comparisons will be performed using Bonferroni correction. The study protocol will be submitted to the local ethics committee for approval, and all participants will provide informed consent.
Interventions
DIAGNOSTIC_TESTTinel's Sign performed at different wrist positions
Participants will undergo the Tinel's Sign at different wrist positions while EMG activity and NCV are recorded to investigate the effect of wrist position on median nerve activity.
Sponsors
Ahram Canadian University
Study design
Observational model
OTHER
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* Healthy individuals aged 18-45 years * No history of hand or wrist pain, neurological or muscular disorders
Exclusion criteria
* Any contraindications to EMG or NCV measurement
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| EMG activity of the thenar muscles during the Tinel's Sign performed at different wrist positions. | Baseline | The amplitude of EMG activity of the thenar muscles will be measured during the Tinel's Sign performed at different wrist positions. The amplitude will be quantified in microvolts (µV). |
| EMG activity of the hypothenar muscles during the Tinel's Sign performed at different wrist positions. | Baseline | The amplitude of EMG activity of the hypothenar muscles will be measured during the Tinel's Sign performed at different wrist positions. The amplitude will be quantified in microvolts (µV). |
| Nerve conduction velocity of the median nerve during the Tinel's Sign performed at different wrist positions. | Baseline | The NCV of the median nerve will be measured during the Tinel's Sign performed at different wrist positions. The NCV will be quantified in meters per second (m/s). |
| Nerve conduction velocity of the ulnar nerve during the Tinel's Sign performed at different wrist positions. | Baseline | The NCV of the ulnar nerve will be measured during the Tinel's Sign performed at different wrist positions. The NCV will be quantified in meters per second (m/s). |
Countries
Egypt
Contacts
Primary ContactMohamed M ElMeligie, Ph.d
Outcome results
None listed