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Detection of Microplastics and Nanoplastics in Neurosurgery Patients (DT-MiNi)

Presence of Microplastics and Nanoplastics in Neurosurgery Patients

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05968053
Acronym
DT-MiNi
Enrollment
500
Registered
2023-08-01
Start date
2023-09-25
Completion date
2025-12-31
Last updated
2025-01-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Brain Tumor, Carotid Artery Stenosis, Glioma, Intracranial Aneurysm, Intracranial Hemorrhages

Keywords

microplastics, nanoplastics, Intracranial Aneurysm, brain tumor, Carotid Artery Stenosis

Brief summary

Plastic particles are a ubiquitous pollutant in the living environment and food chain, so far, plenty of studies have reported the internal exposure of microplastics and nanoplastics in human tissues and enclosed body fluids. Neurosurgery is the only department that can open the skull. In addition to blood and cerebrospinal fluid, there are brain tissue and tumors in the presence of lesions. Whether any of these microplastics and nanoplastics are present remains a mystery. This prospective observational study will harvest biological samples of neurosurgery patients. The objective of this research is to be able to detect microplastics and nanoplastics on blood and operation samples of neurosurgery patients.

Interventions

DIAGNOSTIC_TESTbiological samples analysis

biological samples analysis

Sponsors

Beijing Tiantan Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

* Age 18-80 years * Any type of neurosurgery

Exclusion criteria

·refusal of the patient to participate

Design outcomes

Primary

MeasureTime frameDescription
microplasticsbaseline, intraoperativeDetection of microplastics in human brain tissue and the blood undergoing neurosurgery
nanoplasticsbaseline, intraoperativeDetection of nanoplastics in human brain tissue and the blood undergoing neurosurgery

Countries

China

Contacts

Primary ContactXiaolin Chen, MD
cxl_bjtth@163.com13810624845
Backup ContactFa Lin, MD
13681107240@163.com13681107240

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026