PTCL
Conditions
Keywords
chidamide, maintenance treatment
Brief summary
The efficacy and safety of chidamide in first-line maintenance therapy for PTCL will be assessed through a retrospective case analysis.
Detailed description
The study design belongs to a retrospective study, collecting information on patients with PTCL who were diagnosed and treated with chidamide as maintenance therapy at our center. The collected data includes age, gender, previous treatment regimens, results of auxiliary examinations (such as blood routine, biochemistry, bone marrow cytology, pathology, flow cytometry, NGS, etc.), as well as PET-CT images. The safety and efficacy of Chidemide as first-line maintenance therapy in PTCL will be analyzed.
Interventions
DRUGchidamide
This subset of patients received chidamide as first-line maintenance therapy.
Sponsors
The First Affiliated Hospital with Nanjing Medical University
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* (1) Age: 18 years and older; (2) Gender: Male/Female; (3) Diagnosed with PTCL; (4) Received chidamide as maintenance therapy after first-line treatment.
Exclusion criteria
* (1) Patients with other types of lymphomas; (2) Pregnant women.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| PFS | 2 years | progression free survival |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| OS | 2 years | overall survival |
| CR | 2 years | complete remission |
| DOR | 2 years | duration of remission |
Countries
China
Contacts
Primary Contactwei xu
Outcome results
None listed