Injectable Plasma-rich Fibrin Versus Low-Level Laser Therapy on Othodontic Movement
Conditions
Brief summary
The present prospective clinical study will be undertaken for assessment of the effect of application of Injectable plasma-rich fibrin versus Low-Level Laser Therapy onthe rate of different orthodontic tooth movements,
Detailed description
The present prospective clinical study will be undertaken for assessment of the effect of application of Inject able plasma-rich fibrin versus Low-Level Laser Therapy on the rate of different orthodontic tooth movements, namely: canine retraction, mandibular incisors leveling and alignment, maxillary molar distalization and maxillary incisor intrusion.
Interventions
COMBINATION_PRODUCTLow-level Laser Therapy vs. Injectable Platelets-rich Fibrin
laser and platelet rich fibrin
Sponsors
Al-Azhar University
Study design
Allocation
RANDOMIZED
Intervention model
FACTORIAL
Primary purpose
BASIC_SCIENCE
Masking
NONE
Intervention model description
Factorial Assignment
Eligibility
Sex/Gender
ALL
Age
15 Years to 22 Years
Healthy volunteers
Yes
Inclusion criteria
A- leveling and alignment Eligibility criteria 1. Complete permanent dentition (third molars not included). 2. Moderate mandibular anterior crowding (with Little's irregularity index score greater than 4 mm) who required nonextraction approach in the mandibular arch. 3. No tooth size, shape or root abnormalities visible on patient's radiographic records. 4. No spaces in the mandibular arch. 5. No blocked out tooth that did not allow for placement of the bracket at the initial bonding appointment. 6. No required management with interproximal stripping, intermaxillary elastics, open NiTi springs, and removable or extra-oral devices. Maxillary molar distalization Inclusion criteria: 1\. Age ranges from 14 to 17 years. 2. Bilateral Class II molar relationship. 3. Skeletal Class I or mild Class II relationship. 4. Normal or decreased vertical height. 5. No posterior crowding or spaces. 6. Fully erupted maxillary first and second molars. 7. Congenitally missing or extracted third molars. 8. Good oral hygiene. 9. Absence of any periodontal disease and alveolar bone loss. 10. Absence of medications that may inhibit orthodontic movement * Lower incisor leveling and alignment Inclusion criteria 1. Complete permanent dentition (third molars not included); 2. Moderate mandibular anterior crowding (with little's irregularity index score greater than 4 mm) who required non-extraction approach in the mandibular arch; 3. No tooth size, shape or root abnormalities visible on the patient's radiographic records; 4. No spaces in the mandibular arch; 5. No blocked out tooth that did not allow for placement of the bracket at the initial bonding appointment; 6. No required management with interproximal stripping, inter-maxillary elastics, open NiTi springs, and removable or extra-oral devices. Canine retraction Eligibility criteria 1. Age, 15 to 25 years; 2. Class ii division 1 malocclusion with mild or no crowding; 3. No previous orthodontic treatment; 4. No systemic disease that might have affected bone formation or density, such as osteoporosis, hyperparathyroidism, or vitamin d deficiency; 5. Adequate oral hygiene; 6. Probing depth values not exceeding 3 mm across the 7. Entire dentition; 8. Adequate thickness of the attached gingiva (1-2 mm); 9. No radiographic evidence of bone loss
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| assessment of the effect of application of Injectable plasma-rich fibrin versus Low-Level Laser Therapy on the accelration rate of different orthodontic tooth movements by millimeter | 6 months |
Countries
Egypt
Outcome results
None listed