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Extraction Routes of Intraocular Foreign Body

Outcomes of Retained Posterior Segment Intraocular Foreign Body Extraction With Coexisting Cataract Via The Limbus or The Pars Plana Route

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05966545
Acronym
IOFB
Enrollment
48
Registered
2023-07-28
Start date
2022-01-01
Completion date
2023-09-30
Last updated
2023-07-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intraocular Foreign Body

Brief summary

Intra ocular foreign body removal is indicated to avoid further many complications such as retinal detachment, endophthalmitis. The surgical approach for a posterior segment IOFB is pars plana vitrectomy and its extraction either through the pars plana. our study is to compare limbal route versus pars plana route for extraction of posterior segment IOFB associated with cataract as regard to safety and complications.

Detailed description

Penetrating ocular injuries with retained posterior segment intraocular foreign body (IOFB) are relatively common and account for 17% to 41% of ocular injuries. Intra ocular foreign body removal is indicated to avoid further many complications such as retinal detachment, endophthalmitis, retinal toxicity (secondary to chalcosis, siderosis) and sympathetic ophthalmia. The surgical approach for a posterior segment IOFB is pars plana vitrectomy (PPV) and its extraction either through the pars plana or the limbus. PPV and IOFB extraction through sclerotomy is the most commonly used approach. Most commonly retained posterior segment intra ocular foreign bodies (IOFB) are removed after enlarging one of the sclerotomy ports during pars plana vitrectomy. Intra operative complications reported during IOFB extraction were hypotony, vitreous hemorrhage, incarceration of the retina in the wound, IOFB slippage. Reported post-operative complications were glaucoma and retinal detachment. Incidence of post-operative RD was reported to range from 22% to 79% with poor visual outcomes in most cases PPV and IOFB extraction through the limbal route is an alternative approach to remove IOFB. Complications reported were less frequent and include microscopic hyphema and vitreous hemorrhage. The incidence of post-operative retinal detachment after IOFB extraction through limbus was reported to range from 7.15% to 27.7 % The limbal route for retained posterior segment IOFB extraction can offer the following advantages: it allows visually controlled delivery of the IOFB from the posterior pole to the limbal exit and it has no relation to the vitreous base, thus minimizing the risk of creating a peripheral retinal break during extraction of intraocular foreign body, in contrast to the hidden part behind the iris when using the pars plana route.

Interventions

PROCEDUREpars plana vitrectomy and intraocular foreign body removal

removal of vitreous body and attachment to foreign body then extraction of foreign body

Sponsors

Zagazig University
Lead SponsorOTHER_GOV

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Healthy volunteers
Yes

Inclusion criteria

* Eyes with retained posterior segment intraocular foreign body associated with crystalline lens injury. * Eyes with retained posterior segment intraocular foreign body associated with coexisting cataract.

Exclusion criteria

* Eyes with pre-operative retinal detachment * Eyes with retained posterior segment IOFB with clear lens. * Anterior segment IOFBs * Severely damaged eyes with an initial visual acuity of no light perception where enucleation is the primary treatment * Patients with severely traumatized cornea which can affect visualization during vitrectomy. * Pseudophakic eyes. * Eyes with endophthalmitis

Design outcomes

Primary

MeasureTime frameDescription
post-operative retinal detachment1, 3 and 6 monthscomparing incidence of post-operative retinal detachment after intraocular foreign body extraction via limbus versus pars plana route.

Secondary

MeasureTime frameDescription
post-operative best corrected visual acuity1, 3 and 6 monthsreport post-operative best corrected visual acuity after intraocular foreign body extraction via limbus versus pars plana route.
associated intra operative and post-operative complications.1, 3 and 6 monthsreport associated intra operative and post-operative complications

Countries

Egypt

Contacts

Primary ContactAbbas A. Ali Hashem, MSc
aaahashem@medicine.zu.edu.eg01066227749
Backup ContactWael M. El haig, MD
waelmohamed@medicine.zu.edu.eg01222155744

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026