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Determinants of Functional Capacity in Children With Asthma

Determinants of Functional Capacity in Children With Asthma

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05963919
Enrollment
100
Registered
2023-07-27
Start date
2023-01-01
Completion date
2023-06-30
Last updated
2023-07-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Asthma in Children

Brief summary

The primary aim of this study is to compare the respiratory function, respiratory muscle strength, functional capacity, and lower extremity strength of children with asthma and healthy children in the same age group. The secondary aim of our study is to determine the determinants of functional capacity in children with asthma.

Interventions

OTHER6-minute walk test

Functional capacity will be assessed with the 6-minute walk test (6MWT). 6MWT will be performed in accordance with the criteria of the American Thoracic Society. The 6MWT distance will be recorded in meters.

OTHERPulmonary function test

Pulmonary function test will be performed with a spirometer (COSMED Pony FX (COSMED; Italy) by ATS/ERS criteria. Forced expiratory volume in 1 second (FEV1) and peak expiratory volume (PEF) parameters will be measured. The results will be recorded both as a percentage of measured values and expected values.

Respiratory muscle strength will be measured in accordance with ATS/ERS criteria using an electronic, mobile, (MicroRPM, Micro Medical; UK) intraoral pressure measuring device. Maximal inspiratory pressure (MIP) and maximal expiratory pressure (MEP) values will be recorded. Three measurements will be repeated for each maneuver and the highest value recorded as cmH2O.

OTHERLower extremity muscle strength test

The 30-Second Chair Test is administered using a folding chair without arms, with a seat height of 17 inches (43.2 cm). The chair, with rubber tips on the legs, is placed against a wall to prevent it from moving. The participant is seated in the middle of the chair, back straight; feet approximately a shoulder width apart, and placed on the floor at an angle slightly back from the knees, with one foot slightly in front of the other to help maintain balance. Arms are crossed at the wrists and held against the chest. The participant is encouraged to complete as many full stands as possible within 30 seconds. The participant is instructed to fully sit between each stand.

Sponsors

Atlas University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
6 Years to 17 Years
Healthy volunteers
Yes

Inclusion criteria

Asthma Group Inclusion Criteria: * Being between the ages of 6-17 * Being diagnosed with asthma * Able to walk, cooperate and clinically stable * Being a volunteer to participate in the study * To be able to speak, read, understand, and cooperate in Turkish Asthma Group

Exclusion criteria

* History of previous lung or liver transplant * Having an acute exacerbation and/or a history of hospitalization in the last 1 month * Having diagnosed orthopedic problems affecting mobility or a history of musculoskeletal surgery Control Group Inclusion Criteria: * Being between the ages of 6-17 * To be able to speak, read, understand, and cooperate in Turkish * Being a volunteer to participate in the study Control Group

Design outcomes

Primary

MeasureTime frame
6-minute walk test15-20 minutes
Forced expiratory volume in 1 second (FEV1)10-15 minutes
Peak expiratory flow (PEF)10-15 minutes
Maximal inspiratory pressure (MIP)15-20 minutes
Maximal expiratory pressure (MEP)15-20 minutes
Lower extremity muscle strength5-10 minutes

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026