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Determining Developmental and Clinical Markers Affecting Urinary Function of Children With Spinal Dysraphism

Determining Developmental and Clinical Markers Affecting Urinary Function of Children With Spinal Dysraphism: A Multicenter, Retrospective Cohort

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05962086
Enrollment
1500
Registered
2023-07-27
Start date
2022-10-22
Completion date
2024-12-31
Last updated
2023-07-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spinal Dysraphism

Keywords

Spina Bifida, Neurogenic Bladder, Neurogenic Detrusor Overactivity, Detrusor Overactivity, Incontinence

Brief summary

To identify developmental and clinical biomarkers that affect urinary incontinence at the ages of 5, 7, and 10 according to different neuro-urological clinical factors.

Detailed description

This retrospective observational cohort study aims to identify developmental and clinical biomarkers that affect urinary incontinence at the ages of 5, 7, and 10 according to the types of spinal dysraphism, conus medullaris location, and urodynamics test results.

Interventions

None listed

Sponsors

Asan Medical Center
CollaboratorOTHER
Severance Hospital
CollaboratorOTHER
Samsung Medical Center
CollaboratorOTHER
Keimyung University Dongsan Medical Center
CollaboratorOTHER
Pusan National University Yangsan Hospital
CollaboratorOTHER
Seoul National University Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
No minimum to 10 Years
Healthy volunteers
No

Inclusion criteria

\- Those who received spinal dysraphism diagnosis (ICD Code: Q05.1-05.9) and have been following up and receiving treatments due to neurogenic bladder.

Exclusion criteria

\- As the study is a retrospective study, there is no

Design outcomes

Primary

MeasureTime frameDescription
Achieving full continence at age 5Age 5Achieving full urinary and fecal continence at age 5
Achieving full continence at age 7Age 7Achieving full urinary and fecal continence at age 7.
Achieving full continence at age 10Age 10Achieving full urinary and fecal continence at age 10

Countries

South Korea

Contacts

Primary ContactKwanjin Park, MD/PHD
urodori9@snu.ac.kr+82-2-2072-0695
Backup ContactLouis Kim, BS
kim.hyunkyu11@gmail.com+82-10-4201-0636

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026