Insulin Resistance
Conditions
Brief summary
This study will be conducted to investigate the Effect of whole-body vibration on insulin resistance in obese postmenopausal women
Detailed description
The prevalence of obesity has tripled over the past four decades, imposing an enormous burden on people's health. Obesity is associated with premature mortality and is a serious public health threat that accounts for a large proportion of the worldwide non-communicable disease burden, including type 2 diabetes, cardiovascular disease, hypertension, and certain cancers. reported that Whole-body vibration (WBV) training has been established as a useful method to improve physical fitness in obese individuals. Vibration stimulus during half squatting might suggest a long-term effect of WBV on the endocrine system. Therefore, in this study, The aim to investigate the effect of whole-body vibration on insulin resistance in obese postmenopausal.
Interventions
DEVICETotal body vibration
Whole-body vibration (WBV) training has been established as a useful method to improve physical fitness in obese individuals. Vibration stimulus during half squatting might suggest a long-term effect of WBV on the endocrine system
OTHERmoderate restricted diet
moderate restricted diet
Sponsors
October 6 University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
50 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* All women were postmenopausal with no menses at least 1 year. * Their ages were ranged from 50-60 years old. * Their body mass index (BMI) \> 30 kg/m2. * They were not engaged in any other treatment program.
Exclusion criteria
* Women with body mass index (BMI) \< 30 kg/m2. * Any cardio-respiratory diseases. * Diabetes mellitus. * with malignancy. * with severe hemorrhage, acute viral disease and mental disorders. * Smokers. * Women with life threatening disorders as renal failure
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The Homeostatic model assessment (The HOMA-IR). | up to 3 months | The Homeostatic model assessment (The HOMA-IR). A sample of 5ml of venous blood sample was drawn from all women after 12 hours fasting for measurement of fasting blood glucose, fasting blood insulin and then detection of insulin resistance (by HOMA -IR) through the equation: HOMA-IR=(Glucose ×Insulin)/405 glucose in mass unit (mg/dl) |
| BMI | up to 3 months | Weight and height were measured to detect the BMI according to the following equation: BMI= weight/height² (Kg/m²) |
| Waist circumference | up to 3 months | A non-stretchable tape measurement was used to measure waist circumference for all women in both groups A and B: mid-way between upper border of the lateral iliac crest and the lower border of the lowest rib at the end of gentle expiration with arm relaxed at sides. |
| Skin fold thickness | up to 3 months | Skin fold caliper was used to measure skin fold thickness at abdominal region for all women in both groups A and B |
Countries
Egypt
Outcome results
None listed