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Effects of e-Cigarettes on Perceptions and Behavior - Remote Substudy # 2

Effects of e-Cigarettes on Perceptions and Behavior - Remote Substudy # 2

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05958992
Enrollment
461
Registered
2023-07-25
Start date
2020-08-25
Completion date
2022-05-01
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cigarette Smoking, Cigarette Use, Electronic, Electronic Cigarette Use, Vaping

Keywords

vaping, e-cigarette, vape, nicotine, tobacco

Brief summary

This study assess the ways in which e-cigarette product characteristics, such as flavors and nicotine salts, impact user experience to inform potential regulations.

Detailed description

There are three primary objectives to the study: (1) Determine which dimensions of e-cigarette product diversity differentially affect product appeal in the overall population of tobacco product users as well as affect product appeal across young adult e-cigarette users and middle-age/older adult smokers; (2) Determine which dimensions of e-cigarette product diversity differentially affect product appeal in the overall population of tobacco product users as well as affect abuse liability in young adult e-cigarette users and the ability to resist smoking in adult smokers; (3) Determine the affect of product characteristics on e-cigarette nicotine delivery profile.

Interventions

OTHERE-cigarette

Participants will self-administer experimenter-provided e-cigarettes

Sponsors

University of Southern California
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
DOUBLE (Subject, Investigator)

Intervention model description

Participants will be randomly assigned to use an e-liquid

Eligibility

Sex/Gender
ALL
Age
21 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

Vapers/E-cigarette Users - Regular use of e-cigarettes/vaping devices containing nicotine Cigarette Smokers \- Regular use of cigarettes containing nicotine

Exclusion criteria

* Pregnant or planning to become pregnant

Design outcomes

Primary

MeasureTime frameDescription
Subjective Appeal1 hourThis self-report measures of subjective product appeal will be completed following e-cigarette self-administration. Scores can range from 0 to 100 for the appeal rating, with lower scores representing lower levels of appeal and higher scores representing higher levels of appeal.
Sensory Attributes1 hourThis self-report measures of product sensory attributes will be completed following e-cigarette self-administration. Scores can range from 0 to 100 for the sensory attribute rating, with lower scores representing lower levels of liking the sensory attribute and higher scores representing greater liking of the sensory attribute.
Vaping Delay1 hourMinutes delayed before purchasing time to vape an e-liquid.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026