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Construction of Early Warning Model for the New Psychoactive Substances Using in Adolescents

Early Warning Model Construction on Cognition, Resistance and Using Risk of the New Psychoactive Substances in Adolescents Based on Behavioral Expression of Addiction Susceptibility Genes and Adverse Childhood Experience

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05958641
Enrollment
200
Registered
2023-07-24
Start date
2023-07-17
Completion date
2023-11-30
Last updated
2023-07-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Drug Addiction

Keywords

risk prediction model, NPS, addiction susceptibility genes, adverse childhood experience, adolescents

Brief summary

Based on the biological-psychology-sociological medicine pattern, this study aims to construction an early warning model of the New Psychoactive Substances (NPS) using for adolescents aged 14-35 years old. This study intends to obtain the data related to the behavioral expression of addiction susceptibility genes, adverse childhood experience, cognition, resistance and the use of NPS in adolescents by questionnaire survey (sample size: 200), and then use logistic regression and machine learning to construct an early warning model.

Detailed description

Based on the biological-psychology-sociological medicine pattern, this study aims to construction an early warning model on the use of the New Psychoactive Substances using for adolescents aged 14-35 years old. This study intends to conduct a questionnaire survey (sample size 200) to obtain data related to the behavioral expression of addiction susceptibility genes, childhood adversity experience, cognition, resistance and the use of NPS in adolescents from different regions and different populations. Through data analysis, this study aims to get the weight of different risk factors on NPS use, and then use logistic regression and machine learning to construct an early warning model, so as to screen out high-risk groups. At the same time, the expert group was consulted to establish a risk early warning system to provide a basis for intervention.

Interventions

OTHERQuestionnaires

Participants will be asked to complete the questionnaire including general demographic information, the cognition, resistance and use of NPS as well as the behavioral expression of addiction susceptibility genes and adverse childhood experience.

Sponsors

Wei XIA, PhD
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
14 Years to 35 Years
Healthy volunteers
Yes

Inclusion criteria

* Adolescents aged 14-35 (including 14,35 years old) * Agree to participate in the studies

Exclusion criteria

* Be diagnosed with psychological or mental illness * People that are unconscious, emotionally unstable, or unable to communicate normally * Patients with severe diseases

Design outcomes

Primary

MeasureTime frameDescription
the cognition of NPSBaselineknowledge questionnaire of drug types and risk awareness of drug use will be investigated to know the degree of cognition to NPS
the resistance of NPSBaselinethe drug refusal self-efficacy scale and the drug use permissive attitude will be used to measure the the resistance of NPS
the use of NPSBaselinethere will be some questions to investigate the drug use conditions
Adverse Childhood ExperienceBaselinethe Chinese version of Adverse Childhood Experience Scale with 10 items will be used to measure the adverse childhood experience
hedonic hungerBaselinethe Power of Food Scale with 15 items will be used to measure hedonic hunger
sensation seeking personalityBaselinethe Brief Sensation Seeking Scale for Chinese with 8 items will be used to measure sensation seeking personality
prosocial behaviorBaselinethe Prosocial Tendencies Measure with 26 items will be used to measure prosocial behavior
externalizing behaviorBaseline17 items of aggressive behavior and 15 items of rule-breaking behavior from the Chinese Version of Achenbach Youth Self-Report-2001 Version will be used to measure adolescents' degree of externalizing behavior
sleep qualityBaselinethe Pittsburgh Sleep Quality Index with 9 items will be used to measure adolescents' sleep quality

Countries

China

Contacts

Primary ContactWei Xia, PhD
xiaw23@mail.sysu.edu.cn18823359471

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026