Overweight and Obesity
Conditions
Keywords
physical activity, dietary intervention
Brief summary
The purpose of this study is to determine the effectiveness of a physician led, multi-disciplinary approach to treating obesity that incorporates nutrition (mainly, using genetics to identify appropriate food intake), exercise, and motivational counseling. The investigators plan to recruit overweight/obese (BMI\>25) males and females to participate. Participants will be randomized to receive a personalized diet plan, or a standard care diet plan; both groups will participate in the exercise intervention. For a 6-month duration, both groups will be asked to improve their diet according to their dietary plan and participate in moderate-to-vigorous physical activity (gradual increase up to 300 min/week). The investigators intend to evaluate standard outcomes of weight loss, and assess for any predictors of positive outcomes. Following the six-month intervention, participants will complete a 3-month no contact phase. This no contact phase will provide insight into the effects of the study on weight loss maintenance. Our team also plans to address acceptability by providing evaluations to study participants and conducting interviews with a small subset of participants to improve the intervention for the future.
Interventions
BEHAVIORALNutrigenomix, personalized dietary plan
Personalized dietary plan.
BEHAVIORALPhysical Activity
Participate in an exercise program to work up to 300 min/week of moderate-intensity activity.
BEHAVIORALBehavioral counseling
Review behavioral counseling videos and participate in worksheets to assist with behavioral change.
BEHAVIORALStandard Dietary plan
Receive a standard dietary plan
Sponsors
Augusta University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* Age 18-40 years * BMI \> 25 kg/m2 * No cardiopulmonary disease * stable on medications for 3 months * weight stable (+/-5 pounds) for the past 3 months * Not pregnant or trying to get pregnant * Owns a smartphone * Able to walk unassisted * Not on supplemental oxygen
Exclusion criteria
* Under the age of 18 years * 40 years and older * Unable to participate in an exercise program * Currently pregnant
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Total body weight | 6-months | Use of scale to measure total body weight |
Countries
United States
Contacts
Primary ContactMadison Kindred, PhD
Outcome results
None listed