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Effectiveness of Family-based Intervention for Youn Persons With Eating Disorders

Effectiveness of Family-based Intervention in a Child and Adolescent Mental Health Service for Children and Adolescents With Eating Disorders

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05956366
Acronym
VIBUS-wp1
Enrollment
1000
Registered
2023-07-21
Start date
2018-04-01
Completion date
2037-12-31
Last updated
2024-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Eating Disorders

Keywords

eating disorders, adolescents

Brief summary

This research project aims to characterize a naturalistic cohort of children and adolescents with eating disorders in terms of biological, psychological and psychopathological features. Further, the project will examine the effectiveness of treatment, the determinants of treatment outcome and the course of treatment response for children and adolescents with eating disorders (ED), treated in a generic specialist child and adolescent mental health service. The first choice of treatment is outpatient family-based treatment (FBT), which has documented effect for anorexia nervosa and bulimia nervosa. However, a subgroup of young persons with eating disorders does not respond sufficiently to this treatment, and evidence concerning effective treatment for children and adolescents with atypical eating disorders is still lacking. Further, treatment effectiveness for children and adolescents in a Danish naturalistic setting has never been examined.

Detailed description

The overall aim is to assess associations between patient characteristics and treatment response across the spectrum of eating disorders to identify, which patients benefit from family based treatment, and which patients possibly would need other kinds of treatment or more intensive care. Research questions: 1. Which patient and family characteristics predict faster recovery from ED in childhood and adolescence? 2. Which patient and family characteristics predict intensification of treatment in the forms of day hospital or full hospitalization? 3. At which time point can recovery be predicted based on information from initial assessment and/or assessment during the course of treatment? 4. Which patient and family characteristics (e.g. patterns of comorbid symptoms) are common in those not responding well to treatment within each diagnostic category? 5. How many young patients migrate between ED diagnoses, and what characterizes these patients? 6. Studies on treatment effectiveness for EDNOS in children and adolescents are still lacking. Hence, an important research question of this study is whether family based treatment for EDNOS is effective and is perceived as helpful by patients and families? In addition, the project will seek to answer the following: 7. Is treatment effectiveness in The Capital Region of Denmark (BUC) comparable to published results from other countries in the same age group?

Interventions

Open-end family therapy ad modum The Maudsley model

Sponsors

Mental Health Services in the Capital Region, Denmark
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
7 Years to 17 Years
Healthy volunteers
No

Inclusion criteria

* begin treatment for eating disorder

Exclusion criteria

* lack of informed consent

Design outcomes

Primary

MeasureTime frameDescription
proportion of participants with weight normalisationthrough treatment completion an average of 1 yearat or above 95% of ideal BMI adjusted for age and gender, based on the individual´s prior growth trajectory. BMI is calculated as weight in kg/(height in meters\*height in meters), and percentage if ideal BMI adjusted for age and gender is based on published, standardized growth curves from Danish children and adolescents
proportion of participants with absence of eating disordered behaviorsthrough treatment completion an average of 1 yearabsence for 4 weeks (according to diagnostic questions if Eating Disorder Examination (EDE).

Countries

Denmark

Contacts

Primary ContactMette Bentz, PhD
mette.bentz@regionh.dk+45 38 64 10 35

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026