Bowel Sounds, Crohn Disease, Intestinal Inflammation
Conditions
Keywords
bowel sounds, Intestinal Inflammation, Crohn Disease
Brief summary
The precise and noninvasive evaluation of disease activity among patients with Crohn's disease is not easy, especially for children. It deals with clinical, biological, histological and radiological parameters. Bowel sounds (BS) when evaluated by a stethoscope are modified by several factors including surgery, infection, drugs or intestinal inflammation. These factors can interact on intestinal motricity. There is a direct relationship between gastrointestinal motility and characteristics of BW. The study of BS using a stethoscope is a simple method, although operator dependent and subjective,with a wide inter and intraindividual variability. Some studies among adults showed interest in the spectral analysis of BS to assess gastrointestinal motility. This more precise and reproducible method is not operator dependent. To date, no such study has evaluated the correlation between disease activity and the spectral pattern of BS. of this project is to assess the correlation between disease activity and the spectral pattern of BS in pediatric Crohn's disease.
Interventions
OTHERAbdominal auscultation
spectral analysis of Bowel sounds
Sponsors
Centre Hospitalier Universitaire, Amiens
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
4 Years to 17 Years
Healthy volunteers
No
Inclusion criteria
* Crohn's Disease * Age between 4 and 17 years * Follow-up at CHU Amiens-Picardie
Exclusion criteria
* Other diseases than Crohn's or treatments affecting the gastrointestinal tract, recent (\< 3 months) surgery or refusal to participate (parents or children)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| evaluation of frequency of bowel sounds | one day | — |
| evaluation of wPCDAI | one day | wPCDAI is WEIGHTED PAEDIATRIC CROHN'S DISEASE ACTIVITY INDEX |
| correlation between wPCDAI and frequency of bowel sounds | one day | wPCDAI is WEIGHTED PAEDIATRIC CROHN'S DISEASE ACTIVITY INDEX |
Countries
France
Outcome results
None listed