Different Administration Routes of Dexmedetomidine on Postoperative Delirium

Effect of Different Administration Routes of Dexmedetomidine on Postoperative Delirium in Elderly Patients Undergoing General Anesthesia

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05952050

Enrollment

120

Registered

2023-07-19

Start date

2023-08-01

Completion date

2023-09-30

Last updated

2023-07-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dexmedetomidine, General Anesthesia, Postoperative Delirium

Brief summary

Intravenous dexmedetomidine has been reported to decrease the occurrence of postoperative delirium (POD) in elderly patients. Nevertheless, some previous studies have indicated that intratracheal dexmedetomidine and intranasal dexmedetomidine are also effective and convenient. The current study aimed to compare the effect of different administration routes of dexmedetomidine on POD in elderly patients.

Interventions

DRUGDexmedetomidine

Different Administration Routes of Dexmedetomidine

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

65 Years to 99 Years

Healthy volunteers

Yes

Inclusion criteria

Older than 65 years; General anesthesia for more than two hours;

Exclusion criteria

Design outcomes

Primary

Measure	Time frame
The frequency of delirium during the first 3 postoperative days	3 days

Secondary

Measure	Time frame
The incidence of postoperative sore throat	3 days
The incidence of sleep quality	3 days

Countries

China

Contacts

Primary ContactWeitao Chen

540138690@qq.com18025661798

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026