Knee Osteoarthritis
Conditions
Brief summary
This study aims to determine if baseline measures of psychology and pain sensitivity can predict changes in physical function at 1 year in patients with knee osteoarthritis.
Interventions
DIAGNOSTIC_TESTWOMAC pain subscale
The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Pain Subscale is a self-reported questionnaire that is used to measure pain in people with osteoarthritis (OA). The subscale consists of five items that ask about the intensity, frequency, and duration of pain in the hip and knee joints. The WOMAC Pain Subscale has been shown to be a reliable and valid measure of pain in people with OA. It has been used in a number of clinical trials and is considered to be a standard measure of pain in OA. The WOMAC Pain Subscale is scored on a scale of 0 to 4, with 0 indicating no pain and 4 indicating severe pain. The total score for the subscale is the sum of the scores for the five items. A higher score indicates more pain.
Sponsors
Ahram Canadian University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
40 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Physician diagnosis of knee OA based on clinical and radiographic ACR criteria * Pain in or around the knee on most days of the past month * Aged 40 years or above * Ambulatory with or without walking aid
Exclusion criteria
* Inflammatory arthritis (rheumatoid arthritis, lupus, etc.) * Recent knee injury or surgery (past 3 months) * Severe comorbidity likely to prevent study completion (dementia, terminal illness) * inability to comply with study procedures or follow up
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in Physical Function from Baseline to 1 year (WOMAC) | Change from baseline at 1 year | Assessed using the WOMAC physical function subscale (0-68 scale, higher = worse function) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Pain Catastrophizing Scale | Change from baseline at 1 year | Assessed using the Pain Catastrophizing Scale (0-52 scale, higher = higher catastrophizing) |
| Kinesiophobia | Change from baseline at 1 year | Assessed using the Tampa Scale of Kinesiophobia (17-68 scale, higher = higher kinesiophobia) |
| Change in Sleep Quality from Baseline to 1 year (Pittsburgh Sleep Quality Index) | Change from baseline at 1 year | Assessed using the Pittsburgh Sleep Quality Index (0-21 scale, higher = worse sleep quality) |
| Change in Pain Self-efficacy from Baseline to 1 year (Pain Self-Efficacy Questionnaire) | Change from baseline at 1 year | Assessed using the Pain Self-Efficacy Questionnaire (0-60 scale, higher = stronger self-efficacy beliefs) |
Countries
Egypt
Contacts
Primary ContactMohamed M ElMeligie, Ph.d
Outcome results
None listed