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Effects of E-Cigarettes in Menthol Smokers

Effects of E-Cigarettes in Menthol Smokers

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05949034
Enrollment
19
Registered
2023-07-17
Start date
2019-07-01
Completion date
2020-11-14
Last updated
2023-07-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

E-cigarette Use, Smoking Behaviors

Keywords

menthol, cigarette, smoking

Brief summary

The current laboratory study examines e-cigarette preferences and smoking behaviors in menthol cigarette smokers.

Interventions

DEVICEJUUL E-Cigarette Device

We will use the commercially available and popular JUUL e-cigarette device and e-cigarette solutions.

Sponsors

University of Southern California
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender
ALL
Age
21 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Daily cigarette smoking for at least the past 2 years * Interest in trying e-cigarettes * Report smoking mentholated cigarettes

Exclusion criteria

\-- Pregnancy and/or breastfeeding

Design outcomes

Primary

MeasureTime frameDescription
Mood - Profile of Mood States4 hoursThis measure is obtained through the completion of the Profile of Mood States. A total score will be calculated. Scores can range from 10 to 260, with the lower scores representing lower levels of mood disturbance and higher scores representing higher levels of mood disturbance.
Preference Ratings1 hourSelf-report measures of product preference will be completed following the e-cigarette self-administration. Scores can range from 0 to 100 for the preference rating, with lower scores representing less preference and higher scores representing higher preference.
Mood - Positive Affect Negative Affect Schedule4 hoursThis measure is obtained through the completion of the Positive Affect Negative Affect Schedule. A total score will be calculated for both Positive and Negative Affect. Scores can range from 10 to 50 for both the Positive and Negative Affect, with the lower scores representing lower levels of Positive/Negative Affect and higher scores representing higher levels of Positive/Negative Affect.
Cigarette Craving4 hoursThis measure is obtained through the completion of the Brief Questionnaire of Smoking Urges. A total score will be calculated. Scores can range from 10 to 70, with the lower scores representing a lower level of cigarette craving and higher scores representing greater levels of cigarette craving.
Nicotine Withdrawal - Minnesota Nicotine Withdrawal Scale4 hoursThis measure is obtained through the completion of the Minnesota Nicotine Withdrawal Scale. A total score will be calculated. Scores can range from 0 to 32, with the lower scores representing a lower level of nicotine withdrawal and higher scores representing greater levels of nicotine withdrawal.
Nicotine Withdrawal - Wisconsin Smoking Withdrawal Scale4 hoursThis measure is obtained through the completion of the Wisconsin Smoking Withdrawal Scale. A total score will be calculated. Scores can range from 0 to 112, with the lower scores representing a lower level of nicotine withdrawal and higher scores representing greater levels of nicotine withdrawal.
Smoking Motivation2 hours after experimental session outsetThis measure is obtained through the completion of a computerized behavioral task.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026