Effects of Dexamethasone on Common Bile Duct Cannulation Time

Can Deep Common Bile Duct Cannulation Time During Endoscopic Retrograde Cholangiopancreatography Be Shortened by Dexamethasone

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05945797

Enrollment

Registered

2023-07-14

Start date

2023-08-01

Completion date

2024-05-16

Last updated

2025-03-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Common Bile Duct Calculi, Common Bile Duct Dilatation, Common Bile Duct Diseases, Common Bile Duct Neoplasms, Common Bile Duct Stricture

Keywords

ERCP, Steroids, Dexamethasone, CBD cannulation time

Brief summary

The main aim of this clinical trial is to evaluate the effects of dexamethasone on common bile duct cannulation time during endoscopic retrograde cholangiopancreatography (ERCP) in patients with biliary pathologies. The study will also study the effects of dexamethasone on total procedure time and total fluoroscopy time during ERCP. Participants will be divided into two groups, treatment group and placebo group. Patients in treatment group will receive dexamethasone and those in placebo group will be given normal saline before undergoing ERCP. The results in both groups will be compared to determine the effects of dexamethasone.

Interventions

DRUGDexamethasone 4mg

An injection of 4mg of dexamethasone will be given to patients approximately 2 to 4 hours prior to the procedure of ERCP.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

TRIPLE (Subject, Caregiver, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Age: 18 years or above * Both genders, male and female patients

Exclusion criteria

* Age younger than 18 years or below * Pregnant females * Pre existing stent in CBD or pancreatic duct * Previous history of ERCP * Patients with billroth II surgery * Anatomical abnormalities * Lack of competence in patients * Roux en Y gastric bypass * Patients with contra indications for steroids like DM

Design outcomes

Primary

Measure	Time frame	Description
Shortening of CBD cannulation time	CBD cannulation time will be calculated from the start of the procedure (0 minutes) till complete CBD cannulation has been achieved through catheter and confirmed by fluoroscopy or procedure abandoned if unsuccessful cannulation by 30 minutes.	To determine the effects of dexamethasone on shortening of CBD cannulation time

Countries

Pakistan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026