Nocturnal Polyurea in Patients With BPH
Conditions
Brief summary
In this study investigators will add desmopressin for treatment of patients with benign prostatic hyperplasia and nocturnal polyurea
Detailed description
Investigators will give a group of patients tamsulosin and desmopressin and the other group will take tamsulosin and placepo and compare the outcome regarding symptoms of being prostatic hyperplasia especially nocturia and the effect on nocturnal polyurea in patients
Interventions
DRUGPlacebo
This arm will receive tamsulosin and placebo
This arm will receive tamsulosin and desmopressin acetate daily a
Sponsors
Mansoura University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
MALE
Age
50 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
Men with BPH Age more than 50years Patients with nocturia (2voids per night or More) Patients with nocturnal polyurea (urine volume More than 33%of urine allover the day) IPSS more than 12 Obstructed flow curve Post voiding residual less than 150
Exclusion criteria
* men with BPH with : Acute urine retention Neurogenic bladder dysfunction Cardiovascular disease Hyponatremia Urethral stricture Bladder calculi Prostate cancer
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change of symptoms and nocturia disappears or improve | Follow up for 6 months | Investigators will compare symptoms in the pretreatment period and follow up symptoms following treatment and record the outcome |
Countries
Egypt
Contacts
Primary ContactAhmed Azmy, Resident
Outcome results
None listed