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The Surem TRAF3IP2 Level and Atherosclerotic Plaque Development in Human

The Surem TRAF3IP2 Level and Atherosclerotic Plaque Development in Human

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05945394
Enrollment
800
Registered
2023-07-14
Start date
2023-09-01
Completion date
2023-12-31
Last updated
2023-09-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Heart Disease, Susceptibility to, 1

Keywords

TRAF3IP2, Coronary angiography, coronary deart disease

Brief summary

To evaluate the association of surem TRAF3IP2 levels with the atherosclerotic plaque development in human

Detailed description

Previous study had concluded that TRAF3IP2 plays a causal role in atherosclerotic plaque development and vulnerability in mice. However, no human data was available. In the present study, patients who receive coronary angiography will be enrolled. Their surem TRAF3IP2 levels will be tested using ELASA. The association of surem TRAF3IP2 levels with the atherosclerotic plaque will be evaluated.

Interventions

OTHERNo intervention

This is an obvertional study, and there is no intervention.

Sponsors

Nanjing Medical University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No

Inclusion criteria

1. Patients with suspected coronary heart disease 2. patients received coronary angiography

Exclusion criteria

1. NYHA III-IV 2. malignant tumor 3. acute infection 4. thyroid dysfunction

Design outcomes

Primary

MeasureTime frameDescription
stenosis of coronary artery1 weekThe stenosis of coronary artery based on the results of coronary angiography

Secondary

MeasureTime frameDescription
coronary artery calcium1 weekThe coronary artery calcification based on the results of coronary angiography

Countries

China

Contacts

Primary ContactGeng Jin, MD
gj885258@163.com+86-17753124846

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026