Consistency of Carotid Doppler Blood Flow and Thermodilution Technique

The Consistency of Tracking Changes of Cardiac Output by Carotid Doppler Blood Flow and Thermodilution Technique in Cardiac Surgery Patients

Status

Recruiting

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05944146

Enrollment

200

Registered

2023-07-13

Start date

2023-05-31

Completion date

2026-12-31

Last updated

2023-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac Surgery

Keywords

carotid doppler; hemodynamic

Brief summary

Currently, the gold standard method to estimate CO is the thermodilution technique, pulmonary artery catheter (PAC) and PiCCO system included, however, the invasiveness and complexity of the thermodilution technique have limited their usefulness in many clinical scenarios. By measuring the carotid blood flow, continuous carotid doppler technique has been reported to noninvasively estimate cardiac output (CO) and other parameters related to cardiac contractility and fluid status in various cardiovascular disorders. However, to the best of our knowledge, few study has been reported to evaluate the consistency of this technique in cardiac surgery patients. The aim of this study is to evaluate the tracking ability of CO changes measured by continuous carotid doppler technique in cardiac surgery patients, use the thermodilution technique as the referenced.

Interventions

BEHAVIORALpassive leg raising

transfer a patient from semi-recumbent position to supine position with a 45° leg lifting

DRUGDobutamine

infusion dobutamine

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* adult cardiac surgery patients * with thermodilution technique monitoring * mechanical ventilation

Exclusion criteria

* life threatening arrhythmia * severe valve regurgitation * left ventricular ejection fraction less than 30% * patients with mechanical circulatory support

Design outcomes

Primary

Measure	Time frame	Description
cardiac output by continuous carotid doppler blood flow	5minutes after the patients was sedated	measuring cardiac output using continuous carotid doppler blood flow
cardiac output by thermodilution method	5 minutes after the patients was sedated	measuring cardiac output using thermodilution method

Countries

China

Contacts

Primary ContactGuang-wei Hao

hao.guangwei@zs-hospital.sh.cn02164041990

Backup ContactGuo-wei Tu

tu.guowei@zs-hospital.sh.cn02164041990

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 26, 2026