Biomarkers in Concussion

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05943561

Enrollment

100

Registered

2023-07-13

Start date

2023-09-30

Completion date

2024-06-30

Last updated

2023-09-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Concussion, Intermediate, Concussion, Mild, Concussion, Severe

Brief summary

This will be an observational study measuring serum Neurofilament Light Chain concentrations and associated symptoms, with a control branch, and a post-concussion branch.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

14 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

Over 12 years of age Athletes participating on a sports team willing to participate; undergo blood draws either weekly or every two weeks, depending on arm of study.

Exclusion criteria

Existing active neurodegenerative disorder (ie severe TBI) Active peripheral nerve disorder (ie diabetic neuropathy)

Design outcomes

Primary

Measure	Time frame
Normalization of NfL levels	12 weeks

Secondary

Measure	Time frame
Resolution of concussion symptoms	12 weeks

Contacts

Primary ContactEmma Merrill

emma.merrill@medstar.net2028776607

Outcome results