Psoriasis
Conditions
Keywords
Psoriasis, Psoriasis Area and Severity Index, Gamma-Glutamyl Transferase, CRP, Apolipoprotein B
Brief summary
This observational study aims to evaluate new markers to predict disease activity in psoriasis. The main question is SGOT, SGPT, GGT, hs-CRP, and apo B related to disease severity in psoriasis.
Detailed description
Psoriasis patients who had signed an informed consent were assessed for PASI scores and 5 cc of blood was drawn for GGT, hs-CRP, and apo B examinations. A PASI score is a tool used to measure the severity and extent of psoriasis. PASI is an acronym for Psoriasis Area and Severity Index.
Interventions
None listed
Sponsors
Universitas Sebelas Maret
Study design
Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* Clinical diagnosis of Psoriasis
Exclusion criteria
* Heart Failure * Diabetes Mellitus * Kidney Disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Gamma-Glutamyl Transferase | only in admission | Gamma-Glutamyl Transferase was check in admission, reference range for adults is 5 to 40 U/L (units per liter) |
| Apolipoprotein B | only in admission | Apolipoprotein B (ApoB) is the primary apolipoprotein and is the carrier for the following lipids: chylomicrons, low-density lipoprotein ( LDL), very low-density lipoprotein (VLDL), intermediate-density lipoprotein (IDL), and lipoprotein. Unit used in mg/dL |
| High-sensitivity c-reactive protein | only in admission | High-sensitivity C-reactive protein (hsCRP) is a marker of inflammation that predicts incident myocardial infarction, stroke, peripheral arterial disease, and sudden cardiac death. Unit used in mg/L |
| PASI | only in admission | A PASI (The Psoriasis Area and Severity Index) score can range from 0 to 72 |
Countries
Indonesia
Outcome results
None listed