Overweight and Obesity, Sedentary Time, Work-Related Condition
Conditions
Keywords
brief intense exercise, vascular function, cardiorespiratory fitness
Brief summary
The main objective is to measure the effects of intense brief exercise program in the workplace of administrative staff on the cardio-metabolic health
Detailed description
Backgrounds: Very short (\< 1 minute) and intense exercises, entitled exercise-snacks, have been reported to be effective 1) in improving physical fitness over 6 weeks and 2) in improving vascular function and lowering blood glucose levels over one day. These studies were all carried out in the laboratory. The question therefore arises as to whether these acute vascular and metabolic benefits, as well as those on physical fitness, are sustainable over time following a chronic exercise-snacks program applicable in the professional environment to sedentary, overweight people. Aims of this project is therefore to measure the effects of an exercise-snacks type physical activity program in the workplace of administrative staff on the cardio-metabolic health and sedentary behaviour of staff.
Interventions
OTHERExercise-snacks program
Subjects in the exercise-snacks group will perform 4 exercise-snacks sessions per working day for 4 weeks. These sessions will consist of 80 one-to-one walks to be completed as quickly as possible. They will also receive information about their attitudes to physical activity.
Sponsors
University of Avignon
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE (Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
30 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* administrative staff, * age between 30 and 60, * body mass index ≥25kg/m², * sedentary time ≥7h/day, * minimum 3 working days on site, * no known cardiovascular or metabolic pathology, social security affiliation or benefit, * ability and willingness to give free, written and informed consent.
Exclusion criteria
* pregnant or breast-feeding women, * anti-hypertensive treatment, beta-blockers and anti-diabetics, * known contraindications to physical activity (articular, cardiac or other), * exercise-induced asthma, * lack of motivation of subjects posing problems of compliance and adherence to the exercise program, * participation in a study in the preceding 3 months, ongoing participation in a clinical trial.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Changes in aerobic fitness | at inclusion, at the end of the 4-weeks program and 1 month following the end of the program | Aerobic fitness will be assessed via the Chester step test's prediction of VO2max |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Changes in fat mass | between the start and end of the 4-week exercise program and 4 weeks after the program | measured by InBody, in kg |
| Adherence of staff in the experimental group by analyzing accelerometric data. | during the 4-weeks program | Total number of exercise-snacks performed during the 4-week program by analysing accelerometers data |
| Intensity of exercise-snacks | during the 4-weeks program | Heart rate during exercise-snacks in % heart rate max |
| Changes in flow mediated dilation of superficial femoral artery | at inclusion, at the end of the 4-weeks program | measured by echocardiography (Vivid Q, GE) , in % |
| Changes in peak shear rate of superficial femoral artery | at inclusion, at the end of the 4-weeks program | measured by echocardiography (Vivid Q, GE) during hyperemia, in s-1 |
| Changes in nitrate mediated dilation of superficial femoral artery | at inclusion, at the end of the 4-weeks program | by echocardiography (Vivid Q, GE), in % |
| Changes in superficial femoral artery compliance | at inclusion, at the end of the 4-weeks program | by echocardiography (Vivid Q, GE), in mm2 mmHg-1 |
| Changes in carotid intima-thickness | at inclusion, at the end of the 4-weeks program | by echocardiography (Vivid Q) in mm |
| Changes in level of habitual physical activity | between the start and end of the 4-week exercise program and 4 weeks after the program | Physical Activity questionnaire |
| Changes in carotid-femoral pulse wave velocity | at inclusion, at the end of the 4-weeks program | by Sphygmocor, in m.s-1 |
| Changes in post-occlusive skin perfusion | at inclusion, at the end of the 4-weeks program | by Laser Doppler (Perimed), in perfusion unit, in area under the curve, in time to peak |
| Changes in blood pressure | at inclusion, at the end of the 4-weeks program and 1 month following the end of the program | systolic, diastolic, mean and pulsed |
| Changes in mean amplitude of glycemic excursions | one week before the beginning of the program and the first week of the program and the 2 lastest weeks of the program | measured by continuous glucose monitoring (FreeStyle), in mmol.L-1 |
| Changes in heart rate | between the beginning and end of the 4-week exercise program and 4 weeks after the program. | Heart rate at rest, at the end of the Chester step test and during exercise |
| Changes in lean mass | between the start and end of the 4-week exercise program and 4 weeks after the program | measured by InBody, in kg |
| Change in physical activity behaviour at work of staff | between the start and end of the 4-week exercise program. | Theory of planned behavior questionnaire, score range from 20 to 80 with higher scores mean a better outcome. |
| Changes in rating of perceived exertion | between the start and end of the 4-week exercise program and 4 weeks after the program | measured during the Chester test, score range from 7 to 20 with higher scores mean a worse outcome. |
| Changes in carotid compliance | at inclusion, at the end of the 4-weeks program | by echocardiography (Vivid Q) in mm2 mmHg-1 |
Countries
France
Outcome results
None listed