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Cardiovascular Assessment of Pediatric Cancer Survivors

Cardiovascular Assessment of Pediatric Cancer Survivors: Understanding Long-Term Effects and Risks

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05939089
Acronym
CASPER
Enrollment
54
Registered
2023-07-11
Start date
2023-01-01
Completion date
2023-06-22
Last updated
2023-07-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heart Failure, Left Ventricular Dysfunction

Keywords

Childhood Cancer Survivors, Cardiotoxicity, cancer treatment related heart diseases

Brief summary

The goal of this observational study is to evaluate cardiac and vascular health status of pediatric cancer survivors.

Detailed description

All pediatric cancer survivors were evaluated with cardiological examination, ECG, transthoracic echocardiography (transesophageal echocardiography when required), NT-proBNP, cTnI, kidney function tests, liver function tests, fasting blood glucose, cholesterol panel, iron, iron binding capacity, ferritin, transferrin saturation, B12, vitamin D, folic acid, urinanalysis, hemogram and a questionnaire about living with heart failure.

Interventions

DIAGNOSTIC_TESTECG, Echocardiography, cTnI, NT-ProBNP

All pediatric cancer survivors are evaluated with cardiological examination, ECG, transthoracic echocardiography (transesophageal echocardiography when required), NT-proBNP, cTnI, kidney function tests, liver function tests, fasting blood glucose, cholesterol panel, iron, iron binding capacity, ferritin, transferrin saturation, B12, vitamin D, folic acid, urinanalysis, hemogram and a questionnaire about living with heart failure.

Sponsors

Istanbul University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Diagnosed cancer at pediatric age

Exclusion criteria

* Having cancer after 18 years of age

Design outcomes

Primary

MeasureTime frameDescription
Rate of LV DysfunctionFrom the first visit at cardio-oncology division through study completion, an average of 2 yearsEchocardiographic evaluation of left ventricular functions

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026