Obstetric Anesthesia Problems, Placenta Accreta
Conditions
Keywords
fibrinogen concentrate, obstetric anesthesia, plasenta acreata spectrum, postpartum hemorrhage
Brief summary
The aim of this study is to evaluate the relationship between fibrinogen use and bleeding in patients who underwent cesarean section with a prediagnosis of PAS. The key question(s) it aims to answer are: \[Does the use of fibrinogen concentrate reduce bleeding in PAS patients?\] Patients who had a cesarean section with a pre-diagnosis of PAS were analyzed retrospectively. The choice of anesthesia applied to the patients and the relationship between the use of blood products and bleeding were evaluated.
Detailed description
Our study was designed as a retrospective randomized study. Patients aged 20-50 years and \>34 weeks of gestation who accepted the birth with a cesarean section with a pre-diagnosis of PAS were evaluated retrospectively. examined. were randomized into 2 groups, 53 patients in each group: group1: GNF : the group without fibrinogen concentrate Group 2: GF: the group with fibrinogen concentrate
Interventions
PROCEDUREthe group without fibrinogen concentrate (GNF) , the group with fibrinogen concentrate (GF)
the group without fibrinogen concentrate (GNF, ) the group with fibrinogen concentrate (GF)
Sponsors
Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Masking description
retrospective randomized study
Intervention model description
retrospective randomized study
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 50 Years
Healthy volunteers
Yes
Inclusion criteria
* 20-50 years PAS pre-diagnosed pregnant women * \>34 weeks of pregnancy * Those with normal renal functions
Exclusion criteria
* Patients with renal insufficiency * Those with \<34 weeks of gestation * Pregnant women with missing data
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Laboratory hemoglobin level(g/dl) | Change from preoperative to postoperative day 1(POD 1) hemoglobin values (g/dl). | Our primary aim was to evaluate the postoperative day 1(POD 1) hemoglobin values(g/dl). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| The intensive care unit (ICU) admission and length of stay. | postoperatively up to 1 months | The secondary aim was to investigate the intensive care unit (ICU) admission and length of stay. |
Countries
Turkey (Türkiye)
Outcome results
None listed