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Multicenter Retrospective Observational Study of Acute Myocarditis in Korea

Multicenter Retrospective Observational Study to Investigate the Characteristics and Prognosis of Patients With Acute Myocarditis in Korea

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05933902
Enrollment
841
Registered
2023-07-06
Start date
2022-04-12
Completion date
2023-01-25
Last updated
2023-07-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Myocarditis Acute

Brief summary

In this study, the investigators analyze the clinical characteristics and prognosis of patients with acute myocarditis in South Korea

Detailed description

Acute myocarditis refers to a condition in which inflammatory cells infiltrate the heart muscle due to various causes. Until now, there is no clear treatment method for myocarditis itself, and when myocardial function deteriorates or arrhythmia occurs due to myocarditis, it is common to wait for natural recovery while performing general supportive treatment for heart failure. Through this study, the investigators analyze the factors contributing to the long-term prognosis, myocardial recovery rate, and clinical course of myocarditis. And, the investigators plan to establish an appropriate treatment strategy necessary to increase the survival rate of patients with myocarditis.

Interventions

None listed

Sponsors

Chonnam National University Hospital
CollaboratorOTHER
Sejong General Hospital
CollaboratorOTHER
Keimyung University Dongsan Medical Center
CollaboratorOTHER
Korea University Anam Hospital
CollaboratorOTHER
Asan Medical Center
CollaboratorOTHER
Samsung Medical Center
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* Typical myocarditis symptom and sign, such as fever, chest pain, chest discomfort or shortness of breath, accompanied by elevated myocardial enzymes * The above condition is satisfied and additional information is obtained through imaging such as cardiac MRI or cardiac biopsy

Exclusion criteria

● Coronary artery disease

Design outcomes

Primary

MeasureTime frameDescription
Rate of In hospital mortalitythrough study completion, an average of 1 yearIn hospital death by any cause

Secondary

MeasureTime frameDescription
Rate of all-cause mortalitythrough study completion, an average of 1 yearDeath by any cause during follow-up
Requirement of cardiac replacement therapythrough study completion, an average of 1 yearLeft ventricular assist device insertion or heart transplantation during follow-up
Rates of Re-hospitalization due to any causethrough study completion, an average of 1 yearRe-hospitalization due to any cause during follow-up

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 7, 2026