Rectal Cancer
Conditions
Brief summary
The Intersphincteric resection (ISR) technique is an alternative for anal preservation in ultra-low rectal cancer. The transanal total mesorectal excision (TaTME) technique might compensate for the deficiencies of ISR in terms of tumor spillage and poor surgical field exposure. Thus, the investigators perform ISR through a transanal endoscopic approach (taE-ISR), seeking to evaluate the value of this innovative technique in anal preservation in ultra-low rectal cancer.
Interventions
PROCEDUREtransanal endoscopic ISR
perform ISR using laparoscopy through transanal port
Sponsors
Shanghai Minimally Invasive Surgery Center
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Age between 18 and 75 years * American Society of Anesthesiologists (ASA) score I to III * A biopsy proven histological diagnosis of rectal carcinoma * preoperative stage as (y) cT1-3N0-2M0 * lower margin of the tumor less than 5cm from the anus * tumor diameter ≤5cm
Exclusion criteria
* Pregnant or lactating women * Synchronous rectal carcinoma * History of colorectal cancer or other malignant tumors * Clinical evidence of metastasis * Emergency procedure
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| anal preservation rate | 1 year after sugery | No conversion to APR and closure was closed within 1 year after surgery |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| incidence of Defecation disorders | 6 months after surgery | A Wexner score \>10 indicated the existence of defecation dysfunction |
| incidence of positive distal resection margin | 30 days after surgery | A positive distal resection margin (DRM) was diagnosed with the presence of tumor cells within 1mm from the DRM |
Countries
China
Outcome results
None listed