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Incidence of Descemet Membrane Detachment Post GATT by AS OCT

Incidence of Descemet Membrane Detachment Post Gonioscopy-Assisted Transluminal Trabeculotomy by Anterior Segment Optical Coherence Tomography in Patients With Open Angle Glaucoma

Status
Active, not recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05932940
Enrollment
30
Registered
2023-07-06
Start date
2022-12-01
Completion date
2024-05-10
Last updated
2024-03-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Angle Glaucoma Open

Keywords

gonioscopy-assisted transluminal trabeculotomy, Descemet membrane detachment

Brief summary

detection of Incidence of Descemet membrane detachment post gonioscopy-assisted transluminal trabeculotomy by anterior segment optical coherence tomography in patients with open angle glaucoma.

Detailed description

In our study, which should include 30 eyes with OAG who underwent 360 GATT Screening for Descemet Membrane Detachment will be done by Anterior Segment Optical coherence Tomography using SD-OCT: Optovue RTVue (Optovue Inc., Fremont, CA, USA) for the angle day 1 post operative for all patients and 1 week post operative in cases with Descemet membrane detachment to check for spontaneous resolution. One month post-operative the patients underwent * Best corrected visual acuity (BCVA) using decimal. * IOP measurement using GAT.

Interventions

Ab interno angle surgery one of MIGS to lower IOP

Sponsors

Cairo University
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE

Intervention model description

detection of incidence of Descemet membrane detachment post gonioscopy-assisted transluminal trabeculotomy by anterior segment optical coherence tomography in patients with open angle glaucoma.

Eligibility

Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No

Inclusion criteria

1. Age 18 - 70 years. 2. Patients with open angle glaucoma undergoing gonioscopy assisted transluminal trabeculotomy.

Exclusion criteria

1. Patients with with open angle glaucoma and aphakia. 2. Patients with Congenital Glaucoma. 3. Patients with open angle glaucoma undergoing phaco -gonioscopy-assisted transluminal trabeculotomy. 4. Patients with neovascular glaucoma. 5. Patients with pigmentary Glaucoma.

Design outcomes

Primary

MeasureTime frameDescription
Incidence of Descemet Membrane detachment post GATT4 monthsIncidence of Descemet membrane Detachment post Gonioscopy-Assisted Transluminal Trabeculotomy

Secondary

MeasureTime frameDescription
Amount of reduction of IOP and Glaucoma NGM4 monthsAmount of reduction of intraocular pressure and Number of Glaucoma medications
Incidence of Hyphema post GATT4 monthsIncidence of Hyphema post Gonioscopy-Assisted Transluminal Trabeculotomy
Incidence of Descemet membrane detachment post gonioscopy-assisted transluminal trabeculotomy by anterior segment optical coherence tomography in patients with open angle glaucoma.4 monthsIncidence of Descemet membrane detachment post gonioscopy-assisted transluminal trabeculotomy by anterior segment optical coherence tomography in patients with open angle glaucoma.

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026