Lymphedema
Conditions
Keywords
complete decongestive therapy, carpal tunnel syndrome, upper limb lymphedema
Brief summary
this study will be conducted to investigate the therapeutic effect of complete decongestive therapy on carpal tunnel syndrome post-upper limb lymphedema.
Detailed description
lymphedema is a chronic condition characterized by lymphatic vessel ectasia and valve dysfunction, followed by the reflux of lymphatic fluid into the interstitial space. Lymph stasis may lead to a chronic inflammatory process, resulting in adipose tissue differentiation and fibro adipose tissue deposition. One consequence of post-mastectomy lymphedema may be the development of nerve entrapments. One example is median nerve entrapment in the carpal canal, or carpal tunnel syndrome (CTS). many studies assessed the relationship of CTS as a risk factor for developing lymphedema, other studies stated the possibility of lymphedema as a potential contributor to CTS development. Complex decongestive treatment of breast cancer-related lymphoedema is an accepted strategy and is considered as an international standard for treatment. A previous review concluded that complex decongestive therapy has a positive impact on the volume of arm and quality of life in different stages of lymphedema.sixty females will be allocated randomly to two groups; first one will receive decongestive therapy and the second one will receive the routine medical treatment for ten weeks
Interventions
the patients will receive Complete decongestive therapy in the form of intermittent pneumatic compression, Exercising, bandaging, and manual lymphatic drainage with Pressures of 50, 80, and 120 mmHg and timing 5, 20, and 50 secs
OTHERMedical treatment
the patients will receive routine medical treatment
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Investigator, Outcomes Assessor)
Masking description
opaque sealed envelope
Intervention model description
complete decongestive therapy and routine medical treatment
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 40 Years
Healthy volunteers
No
Inclusion criteria
* Age will range between 20- 40 years. * Only females will participate in the study. * All patients have carpal tunnel syndrome post upper limb lymphedema.
Exclusion criteria
* Diabetes mellitus. * Individuals with cardiopulmonary conditions. * Individuals undergoing radiation therapy or chemotherapy. * Hepatic or pancreatic diseases. * Sensory impairment.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| hand strength | up to ten weeks | hand held dynamometer will be used for measuring the hand strength |
| median nerve conduction velocity | up to ten weeks | median nerve conduction velocity will be measured by electromyography device |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| pain intensity | up to ten weeks | Visual analogue scale which is 100 mm horizontal line will be used for measuring pain intensity. the scale has no pain on the left side and worst pain on the right side |
Outcome results
None listed