Effect of Intravenous Dextrose on PONV in Patients Undergoing Gynecological Laparoscopy

Research Investigator

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05932160

Enrollment

108

Registered

2023-07-06

Start date

2023-06-01

Completion date

2023-12-30

Last updated

2023-11-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Nausea and Vomiting

Keywords

PONV

Brief summary

This study is to explore the relationship between intravenous infusion of dextrose during emergence from anesthesia and the incidence of PONV in patients undergoing gynecology laparoscopy (GL).

Interventions

OTHER5% glucose

Patients in the experimental group were infused intravenously with 5% dextrose (500 ml/h) in the PACU.

OTHERlactated ringers

Patients in the control group were infused intravenously with lactated ringers (500 ml/h) in the PACU.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

TRIPLE (Subject, Caregiver, Outcomes Assessor)

Masking description

Triple (Participant, Care Provider, Outcomes Assessor)

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 75 Years

Healthy volunteers

Inclusion criteria

1. ASA I or II; 2. Performing gynecologic laparoscopic procedures under general anesthesia;

Exclusion criteria

1. age \<18 or \>75 2. severe hypertension,diabetes mellitus, significant hepatic or renal disease 3. inability to follow protocol 4. refusal to participant

Design outcomes

Primary

Measure	Time frame	Description
Postoperative nausea and vomiting	Measured at 0.5 hours postoperatively.	The severity and incidence of PONV at 0.5 hours postoperatively.

Secondary

Measure	Time frame	Description
Consumption of postoperative analgesic	Approximately 24 hours after surgery.	Record the type and dosage of postoperative analgesic within 24 hours after surgery.
Postoperative pain response	Measured at 0.5 hours postoperatively.	The Visual Analog Score was used to assess pain response at 0.5 hours postoperatively. The score ranges from 0 (pain free or no pain) to 10 (worst pain).
Recovery time of PACU	Approximately 24 hours after surgery.	Record PACU recovery time in hours. The criteria for discharge from PACU was the achievement of a modified Aldrete score ≥ 9.
Consumption of postoperative rescue antiemetic	Approximately 24 hours after surgery.	Record the type and dosage of postoperative rescue antiemetic within 24 hours after surgery.

Countries

China

Contacts

Primary ContactJiang Liu, B.S

Time1987fx@163.com17667192336

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026