The Role of Point-of-care Polymerase Chain Reaction in Managing Nosocomial Pneumonia

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05928208

Enrollment

Registered

2023-07-03

Start date

2017-02-01

Completion date

2023-05-30

Last updated

2023-07-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nosocomial Pneumonia

Keywords

polymerase chain reaction

Brief summary

The study compares a device that is used for the detection of bacteria and MDR pathogens from skin, soft tissue and nose with the gold-standard (microbiological lab). It is a novel use for this device because it has been used in samples from the lower-respiratory tract.

Detailed description

The purpose of this study is to find out if a POC-PCR device can be use in the diagnosis of hospital acquired pneumonia and ventilation-associated pneumonia.

Interventions

DIAGNOSTIC_TESTno intervention

no intervention

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* patients that are admitted for at least 48 hours * radiological findings typical for pneumonia * signs of infection

Exclusion criteria

* patient or patient relatives doesn't accept to enter the study

Design outcomes

Primary

Measure	Time frame	Description
To determine the sensibility and specificity of the device GeneXpert in diagnosis of pneumonia	4 years	Comparison between device and gold standard
Utility of POC-PCR in managing pneumonia	4 years	Decision making in pneumonia management

Countries

Romania

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026