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Omega-3 Fatty Acid Supplementation to Enhance Performance

Omega-3 Fatty Acid Supplementation to Enhance Performance in Collegiate Athletes

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05924139
Acronym
FO n-3
Enrollment
33
Registered
2023-06-29
Start date
2023-03-06
Completion date
2023-06-02
Last updated
2023-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Body Composition, Muscle Soreness, Strength

Keywords

omega-3 fatty acid, strength, body composition, muscle soreness

Brief summary

The goal of this intervention study is to determine if omega-3 fatty acid supplementation as compared to placebo improves performance in track and field athletes. The main questions it aims to answer are: 1. Can performance be improved 2. Can strength be enhanced 3. Will positive body composition changes occur (lean vs fat mass) 4. Will feelings of muscle soreness be diminished Participants will take either omega-3 fatty acid supplements or placebo and continue with their sport specific training regimen. Researchers will compare the supplement group to placebo group to determine if there are any significant differences.

Detailed description

This is a randomized, placebo-controlled trial to determine the efficacy of fish oil-derived omega-3 fatty acid supplementation. Up to sixty participants will be randomized to receive one of two conditions: 4.0 grams of FO n-3/day or placebo (coconut oil) for the 10-week protocol study period. Nordic Naturals (Ultimate Omega) will be used as the intervention at a dose of 6 capsules/day (3840 mg total FO/1950 mg EPA/1350 mg DHA). Although protocols have varied among studies with regards to dosage, the proposed regimen was selected based on studies on strength in older adults and college-aged athletes utilizing a range of 2-5g FO n-3 per day. Blinded randomization will be accomplished with a research associate providing every first (of two) participants the placebo, while the second will receive the supplemented condition until recruitment is complete. Participants will be provided their supplement in 2-week increments and instructed to consume with/near their evening meal. Used bottles will be returned after two weeks and participants will receive the next 2-week supply of supplement and the leftover pill count will determine compliance rate. The target population is apparently healthy college athletes (male and female of all ethnicities) between the ages of 18-25 years at Baylor University. Participants must be able to read and understand English and sign their own consent form. Up to 60 subjects will be recruited via direct contact or team briefings with permission of the coaches.

Interventions

DIETARY_SUPPLEMENTOmega-3 fatty acid

6 capsules per day of 3840 mg that included 1950 mg EPA and 1350 mg DHA

DIETARY_SUPPLEMENTPlacebo

4 capsules per day of coconut oil

Sponsors

Baylor University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender
ALL
Age
18 Years to 25 Years
Healthy volunteers
Yes

Inclusion criteria

Apparently healthy college athletes (male and female of all ethnicities) between the ages of 18-25 years.

Exclusion criteria

-Participants will be excluded if they are unable to physically train due to injury/illness or are pregnant, or have a known heart condition or pacemaker.

Design outcomes

Primary

MeasureTime frameDescription
Strengthchange from baseline at 8 weekslower body strength will be evaluated via a counter movement jump
Powerchange from baseline at 8 weekshandgrip strength will be used as a proxy for upper body strength via a dynamometer

Secondary

MeasureTime frameDescription
Body compositionchange from baseline at 8 weeksbioelectrical impedance analysis (BIA), a double-indirect body composition technique based on a 3-component model (fat mass, fat-free mass, and total body water), will be performed.
Muscle sorenesschange from baseline, every 2 weeks and at 8 weeksSubjects will be asked to rate their muscle soreness on a 10-point Likert scale
Omega-3 indexchange from baseline at 8 weeksThe Omega-3 Index provides information on the participants baseline level of EPA/DHA level in the blood

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026