Invasive Mechanical Ventilation ARDS
Conditions
Brief summary
According to the ARDS Berlin definition, patients with severe concurrent invasive mechanical ventilation were selected, and clinical data and prognosis were collected. Samples such as blood and balf were collected for analysis based on changes in the condition.
Interventions
None listed
Sponsors
Chinese PLA General Hospital
Study design
Observational model
COHORT
Time perspective
OTHER
Eligibility
Sex/Gender
ALL
Age
18 Years to 100 Years
Healthy volunteers
No
Inclusion criteria
1. Patients who meet the Berlin definition of ARDS and require invasive mechanical ventilation. ARDS diagnostic criteria: according to the Berlin definition, Chest radiograph shows patchy shadows in the lungs; Respiratory failure cannot be completely caused by heart failure or excessive fluid infusion 2. ARDS onset ≤ 3 days when included in the study 3. Patient PaO2/FiO2 ≤ 200mmHg when included in the study
Exclusion criteria
* 1\) Patients with intracranial hypertension, pleural fistula, pneumothorax, HIV, HBV, HCV 2\) Age\>85 years old or\<18 years old 3\) Pregnant patients 4\) Severe hemodynamic instability (vasopressor increase\>30% in the first 6 hours, or Norepinephrine\>0.5 mg kg/min) 5\) Patients unable to perform EIT ventilation and/or perfusion testing (unable to perform internal jugular vein catheterization, Hypernatremia, chest malformation, active implant device, unstable spinal injury or fracture, skin lesions opposite the EIT monitoring area) 6\) Patients with abnormal esophageal anatomical structure and inability to indwelling gastric tubes 7\) Disagreement for inclusion in this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall Survival | 28 days |
Countries
China
Contacts
Primary ContactLin Wang, doctor
Outcome results
None listed