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Effect of Fermented Products and Probiotics on the Condition of the Implant

Evaluation of Fermented Foods and Probiotic Consumption Frequency in Peri-implant Disease and Health

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05921357
Acronym
EFFPCFPDH
Enrollment
126
Registered
2023-06-27
Start date
2022-07-04
Completion date
2023-03-31
Last updated
2025-02-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Implant

Keywords

Fermented foods, probiotics, peri-implant health, peri-implant mucositis, peri-implantitis

Brief summary

126 individuals with peri-implant disease and health, aged between 18-70 years, who applied to Bolu University Faculty of Dentistry Periodontology Clinic, participated in the study.The inclusion criteria for patient participation in the study were: age of patients between 18 and 70 years; the presence of at least 20 natural teeth in the oral cavity; systemic health. Peri-implant status was determined by the clinician (T.Ş.) by evaluating dental implants' plaque, gingival index, bleeding on probing, pocket depth measurements, and clinical attachment level. In addition, them systemic illness, pregnancy, breastfeeding status, medication, antibiotic use, and whether they smoked were questioned. Systemically unhealthy patients who did not use antibiotics within a month, were breastfeeding or pregnant, had uncontrolled diabetes, rheumatic fever, a history of lung and kidney disorders, and used drugs that could affect periodontal tissues were not included in the study. After examination, the patients were divided into three groups according to their disease: Peri-implantitis (42 patients), peri-implantitis (42 patients), and peri-implant health (42 patients). Demographic characteristics (age, weight, gender, height, education, and employment status) of the participants were collected with a questionnaire. With this survey, fermented foods and probiotic products such as bacon, soy sauce, pickles, sourdough bread, whole grain, rye, wholemeal bread, ayran, kefir, turnip, vinegar (homemade), pomegranate syrup (homemade), probiotic beverage, the frequency and amount of consumption of cheese, dark chocolate, tablets, capsules, chassis, butter and other (Kimchi, sauerkrauth, miso soup, fermented herring, kombucha, etc.) were determined. It was requested to determine the relationship between the health and disease of the implant and the frequency of consumption of fermented and probiotic products and foods in individuals with implants.

Interventions

OTHERQuestionnaire

Questionnaire and examine

Sponsors

Tuğba ŞAHİN
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
FEMALE
Age
18 Years to 70 Years
Healthy volunteers
No

Inclusion criteria

* Systemically healthy individuals * Individuals between the ages of 18-70

Exclusion criteria

* No use of antibiotics within one month * Breastfeeding or being pregnant * Uncontrolled diabetes, rheumatic fever, history of lung and kidney disorders, and drug use that will affect periodontal tissues

Design outcomes

Primary

MeasureTime frameDescription
Periodontal pocket depthBaselinea pathologically deepened gingival sulcus around a tooth at the gingival margin.
Consumption amountBaselineThe average quantity of an item consumed or expended during a given time interval, expressed in quantities by the most appropriate unit of measurement per applicable stated basis.
Consumption frequencyBaselinethe number of times a product is consumed in a given time period.
Bleeding on probingBaselineBleeding, leading sign of inflammation inside the connective tissue, is a critical factor for pocket depth measurements, and with other variable factors prevents making reproducible measurements.
Daily intakeBaselineThe amount of a substance that people can consume on a daily basis

Secondary

MeasureTime frameDescription
Gingival indexBaselineThis measurement is based on the presence or absence of bleeding on gentle probing.
Clinical attachment levelBaselineCAL is calculated by subtracting the gingival margin level from the probing depth.
Plaque indexBaselineThe plaque index assesses the amount of dental plaque visible on the vestibular and lingual surfaces of all teeth

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026